King Fahd Medical Research Center

KFMRC

Neurooncology Translational Research Lab

Mapping of DNA for brain tumors retrieved from King Abdulaziz university hospital patients.

To advance the science of nervous system tumor from genetic and therapeutic aspects

Developing genetic related DNA markers to establish diagnosis prior to surgery

Developing DNA targeted therapeutic medications/ treatment for commonly occurring brain tumors

Baeesa SS, Hussein D, Altalhy A, Bakhaidar MG, Alghamdi FA, Bangash M, Abuzenadah A. Malignant Transformation and Spine Metastasis of an Intracranial Grade I Meningioma: In Situ Immunofluorescence analysis of Cancer Stem Cells. World Neurosurg. 2018 Sep 8. pii: S1878-8750(18)32024-2.
Alamir H, Alomari M, Salwati A, Saka M, Bangash M, Baeesa S, Alghamdi F, Carracedo A, Schulten H, Chaudhary A, Abuzenadah A, Hussein D*. In situ Characterization of Stem Cells-like Biomarkers in Meningiomas. Cancer Cell Int. 2018 May 25;18:77.
Aljuhani SH, Bamaroof SA, Alghamdi TH, Almogbel AA, Alkhammash AS, Alkhammash BS, Bahusayn AA, Bangash MH, Baeesa SS, Chaudhary AG, Abuzenadah AM, Mirza AA, Saka MY, Hussein DM*. Public Awareness of Central Nervous System Tumors in the Kingdom of Saudi Arabia. Neurosciences. 2018 Jul;23(3):227-237.
Schulten HJ, Bangash M, Karim S, Dallol A, Hussein D, Merdad A, Al-Thoubaity FK, Al-Maghrabi J, Jamal A, Al-Ghamdi F, Choudhry H, Baeesa SS, Chaudhary AG, Al-Qahtani MH. Comprehensive molecular biomarker identification in breast cancer brain metastases. J Transl Med. 2017 Dec 29;15(1):269.

Khan I, Baeesa S, Bangash M, Schulten HJ, Alghamdi F, Qashqari H, Madkhali N, Carracedo A, Saka M, Jamal A, Al-Maghrabi J, AlQahtani M, Al-Karim S, Damanhouri G, Saini K, Chaudhary A, Abuzenadah A, Hussein D*.Pleomorphism and drug resistant cancer stem cells are characteristic of aggressive primary meningioma cell lines. Cancer Cell Int. 2017 Jul 21;17:72.
Schulten HJ, Hussein D, Al-Adwani F, Karim S, Al-Maghrabi J, Al-Sharif M, Jamal A, Bakhashab S, Weaver J, Al-Ghamdi F, Baeesa SS, Bangash M, Chaudhary A, Al-Qahtani M. Microarray expression profiling identifies genes, including cytokines, and biofunctions, as diapedesis, associated with a brain metastasis from a papillary thyroid carcinoma. Am J Cancer Res. 2016 Oct1; 6(10):2140-2161.
Schulten HJ, Hussein D, Al-Adwani F, Karim S, Al-Maghrabi J, Al-Sharif M, Jamal A, Al-Ghamdi F, Baeesa SS, Bangash M, Chaudhary A, Al-Qahtani M. Microarray Expression Data Identify DCC as a Candidate Gene for Early Meningioma Progression. PLoS One. 2016 Apr 20; 11(4):e0153681.
Khan I, Bangash M, Baeesa S, Jamal A, Carracedo A, Alghamdi F, Qashqari H, Abuzenadah A, AlQahtani M, Damanhouri G, Chaudhary A, Hussein D*. Epidemiological Trends of Histopathologically WHO Classified CNS Tumors in Developing Countries: Systematic Review. Asian Pac J Cancer Prev. 2015; 16(1):205-16.