مركز الملك فهد للبحوث الطبية

KFMRC

kfmrc@kau.edu.sa

(25027 ,61453) 00966-12-695-2000

عن الوحدة الإنجاز العلمي فريق العمل التعليم اتصل بنا

وحدة أمراض الدم

وحدة أبحاث أمراض الدم مختصة بالأبحاث السريرية وما قبل السريرية لتطوير الخدمات التشخيصية والعلاجية لأمراض وأورام الدم.

حيث يعنى الباحثون المختصون في هذه الوحدة بعدة مجالات في أمراض الدم لتشمل أمراض واعتلالات الهيموجلوبين بالإضافة إلى سيولة الدم والجلطات. تهتم الوحدة بدراسة طب نقل الدم، وأورام الدم كما تعمل على دراسة طرق وفعالية العلاج بالخلايا الجذعية والمناعية.

المجالات البحثية

أمراض واعتلالات الهيموجلوبين.
سيولة الدم والجلطات.
طب نقل الدم.
أورام الدم والعلاج بالخلايا الجذعية والمناعية.

+93

المنشورات العلمية

+10

الأنشطة العلمية

+3

الجوائز العلمية

+2

التدريب والتعليم

+4

الشراكات

+11

الطلبة

مخرجات الوحدة

الإنجاز العلمي

المنشورات العلمية لعام 2023

Fabrication, assessment, and optimization of alendronate sodium nanoemulsion-based injectable in-situ gel formulation for management of osteoporosis By Wesam H. Abdulaal,Khaled M. HosnyORCID Icon,Nabil A. AlhakamyORCID Icon,Rana B. Bakhaidar,Yasir Almuhanna,Fahad Y. Sabei,Mohammed Alissa,Mohammed Majrashi,Jawaher Abdullah Alamoudi,Mohannad S. Hazzazi,Ayman Jafer &Rasha A. KhallafORCID Icon	1

Phytochemical Characterization and Efficacy of Artemisia judaica Extract Loaded Chitosan Nanoparticles as Inhibitors of Cancer Proliferation and Microbial Growth By by Husam Qanash, Abdulrahman S. Bazaid, Abdu Aldarhami, Bandar Alharbi, Majed N. Almashjary, Mohannad S. Hazzazi, Hashim R. Felemban and Tarek M. Abdelghany	2

Analysis of NPM1 and FLT3 Mutations in Patients with Acute Myeloid Leukemia in Jeddah, Saudi Arabia: A Pilot Study By Raed Alserihi, Hameeda Ahmad, Heba Alkhatabi and Talal Qadah	3

Enhanced Solubility and Biological Activity of Dexibuprofen-Loaded Silica-Based Ternary Solid Dispersions by Muhammad Asim, Marriam Nazir, Zunera Chauhdary, Muhammad Irfan, Syed Haroon Khalid, Sajid Asghar, Usra, Raed I. Felimban, Mohammed A Majrashi, Mohannad S. Hazzazi, Mohammed Alissa, Safa H Qahl, Ghulam Hussain, Azhar Rasul, Shahzad Ali Shahid Chatha and Ikram Ullah Khan	4

Evaluation of Antidiabetic, Antioxidant and Anti-Hyperlipidemic Effects of Solanum indicum Fruit Extract in Streptozotocin-Induced Diabetic Rats by Manoj M. Gadewar, Prashanth G K, Prabhu Chandra Mishra, Ghulam Md Ashraf, Majed N. Almashjary, Steve Harakeh, Vijay Upadhye, Abhijit Dey, Pallavi Singh, Niraj Kumar Jha and Saurabh Kumar Jha	5

Potential Regulation of miRNA-29 and miRNA-9 by Estrogens in Neurodegenerative Disorders: An Insightful Perspective by Mahmoud A. Ebada, Abdalrhman Mostafa, Al-Hussein A. Gadallah, Souad Alkanj, Badrah S. Alghamdi, Ghulam Md Ashraf, Adel M. Abuzenadah, Raed F. Alserihi, Ahmed Wadaa-Allah and Mohamed Salama	6

Lack of Evidence on Association between Iron Deficiency and COVID-19 Vaccine-Induced Neutralizing Humoral Immunity by Arwa A. Faizo, Asma A. Bawazir, Majed N. Almashjary, Ahmed M. Hassan, Fadi S. Qashqari, Ahmed S. Barefah, Sherif A. El-Kafrawy, Thamir A. Alandijany and Esam I. Azhar	7

Impact of COVID-19 Pandemic on Treatment Decisions of Patients Treated by Hematologists in Saudi Arabia by SalemM Bahashwan, Hatem Alahwal, AbdullahT Almohammadi, Osman Radhwi, ShahidaA Khan and Ahmed Barefah	8

Metabolomics: A New Era in the Diagnosis or Prognosis of B-Cell Non-Hodgkin’s Lymphoma by Abdullah Alfaifi, Mohammed Y. Refai, Mohammed Alsaadi, Salem Bahashwan, Hafiz Malhan, Waiel Al-Kahiry, Enas Dammag, Ageel Ageel, Amjed Mahzary, Raed Albiheyri, Hussein Almehdar and Ishtiaq Qadri	9

Incidence and Risk Factors of Infections Among Diffuse Large B-cell Lymphoma and Classical Hodgkin’s Lymphoma Patients in a Tertiary Care Center in Saudi Arabia: A Retrospective Cohort Study by Rakan H. Alelyani, Ali H. Alghamdi, Thamer A. Almughamisi, Abdulrahman M. Alshareef, Abdulaziz N. Kadasa, Amir M. Alrajhi, Abdullah K. Alburayk, Ahmed S. Barefah, Osman O. Radhwi, Abdullah T. Almohammadi, Salem M. Bahashawan, Hatem M. AlAhwal	10

The Influence of Prenatal Exposure to Methamphetamine on the Development of Dopaminergic Neurons in the Ventral Midbrain by Walaa F. Alsanie, Sherin Abdelrahman, Raed I. Felimban, Heba A. Alkhatabi, Ahmed Gaber, Ebtisam Abdulah Alosimi, Majid Alhomrani, Hamza Habeeballah, Charlotte A. E. Hauser, Abdulhakeem S. Alamri, Aiysha Althobaiti, Abdulaziz Alsharif, Ahmed S. Alzahrani, Mohammad S. Al-Ghamdi, Bassem M. Raafat, Khaled A. Alswat, Yusuf S. Althobaiti and Yousif A. Asiri	11

Anticancer Effects of Honey Varieties on Human Cells by Studying Some Physical Parameters, Hydrogen Peroxide Content, Catalase, Glucose Oxidase, and Microbial Activities by Al-Eisa, Rasha A. 1 ; Ashour, Amal Adnan 2 ; Helal, Mahmoud 3 ; Aljahani, Amani H. 4 ; Kadi, Roqayah H. 5 ; Hazzazi, Mohannad S. 6 ; Sami, Rokayya 7 ;	12

Outcomes of Cholelithiasis Among Patients With Sickle Cell Disease: A Tertiary Care Center Experience by Bushra Almalki, Sultan Banser, Banan Alghamdi, Majed Almalki, Adel Al-Marzouki, Mohammed Alharthi and Osman Radhwi	13

Insights from the molecular docking analysis of EGFR antagonists by Mohammad Azhar Kamal1, Hanadi M Baeissa2, Israa J. Hakeem2, Reem S Alazragi2, Mohannad S. Hazzazi3,4, Tahani Bakhsh5, Akhmed Aslam6, Bassem Refaat6, Elshiekh B. Khidir6, Kadhem Juma Alkhenaizi7 & Qamre Alam7*	14

Outcomes of therapeutic plasma exchange A 15-year tertiary center experience by Hindawi, Salwa1,2,3; Radhwi, Osman1,2,; Badawi, Maha1,2,3; Rajab, Hanaa4; Al Mansouri, Fatma5; Alzahrani, Ali6; Bukhari, Hussam7; Gholam, Kholoud3; Almalki, Ahmad3; Awadh, Abdulaziz3; Yagoub, Ismat Khalil3; Zaher, Galila1,2,	15

Exploration of acute and chronic anti-inflammatory potential of Quercus leucotrichophora A. Camus extracts in Wistar rats: A mechanistic insight by Ammara Saleem, Izza Hameed, Muhammad Furqan Akhtar, Ghulam Md Ashraf, Badrah S. Alghamdi, Md. Habibur Rahman and Majed N. Almashjary	16

Blastocystis sp.—An emerging cause of diarrhea post stem cell transplantation by Osman Radhwi, Abdullah Almohammadi, Adel Almarzouki, Ahmed Barefah, Salem Bahashwan, Hatem Alahwal	17

Increased inflammatory cytokines and oxidative stress enhanced antibody production in breast and prostate cancer patients with COVID-19 related depression by Naif K. Binsaleh1, Subuhi Sherwani, Reem Eltayeb, Husam Qanash, Abdulrahman S. Bazaid, Maryam Althobiti, Mohannad S. Hazzazi and Saravanan Rajendrasozhan	18

Is a Higher Body Mass Index a Risk Factor for Developing Antiphospholipid Antibody Syndrome? by Eman M. Mansory, Atheer M. Badawi, Renad Rajab, Asma Abdullah, Mudhawi Alhiniah, Rakan H. Alelyani, Jamil Al-Mughales, Hatem M. AlAhwal and Ahmed S. Barefah	19

A Saudi multicenter experience on therapeutic plasma exchange for patients with thrombotic thrombocytopenic purpura: A call for national registry by Osman Radhwi MD, Maha A. Badawi MD, Adel Almarzouki MD, Fakhr Al-Ayoubi PhD, Ghada ElGohary MD, Kazi Nur Asfina MD, Abdulrahim Mohammed Basendwah MD, Iman Ayed Alhazmi MD, Eiman A. Almahasnah MD, Ahmed AlBahrani MD, Abdulrahman Al Raizah MD, Ayel Yahya MD, Khadeja Alshahrani MD, Salwa Hindawi MD	20

Transplacental Transfer of SARS-CoV-2 Receptor-Binding Domain IgG Antibodies from Mothers to Neonates in a Cohort of Pakistani Unvaccinated Mothers by Steve Harakeh, Ihsan Alam Khan, Gulab Fatima Rani, Muhammad Ibrahim, Aysha Sarwar Khan , Mohammed Almuhayawi , Rajaa Al-Raddadi, Addisu D. Teklemariam, Mohannad S. Hazzazi, Waleed M. Bawazir, Hanouf A. Niyazi, Turki Alamri , Hatoon A. Niyazi and Yasar Mehmood Yousafzai	21

Immunoprofiling of cytokines, chemokines, and growth factors in female patients with systemic lupus erythematosus– a pilot study by Laila A. Damiati, Iuliana Denetiu, Sami Bahlas, Samar Damiati & Peter Natesan Pushparaj	22

Anti-Helicobacter pylori, Antioxidant, Antidiabetic, and Anti-Alzheimer’s Activities of Laurel Leaf Extract Treated by Moist Heat and Molecular Docking of Its Flavonoid Constituent, Naringenin, against Acetylcholinesterase and Butyrylcholinesterase by Aisha M. H. Al-Rajhi 1,Husam Qanash 2ORCID,Majed N. Almashjary 3,4ORCID,Mohannad S. Hazzazi 3,4ORCID,Hashim R. Felemban 3,5 andTarek M. Abdelghany	23

Promoter Methylation-Regulated Differentially Expressed Genes in Breast Cancer by Sindi S, Hamdi N, Hassan S, Ganash M , Alharbi M, Alburae N, Azhari S, Alkhayyat S, Linjawi A, Alkhatabi H, Elaimi A , Alrefaei G, Alsubhi N, Alrafiah A , Alhazmi S	24

Association of Genetic Variant FVIII Gene and Factor VIII: A Pilot Study Among Hemophilia A Female Relatives in Saudi Arabia by Abdullah T. Almohammadi, Osman Radhwi, Hatem AlAhwal, Ahmed Barefah, Salem Bahashwan, Ibraheem M. Ashankyty, Majed Almashjari, Rawan Ayaz, Adel Al-Marzouki, Galila F. Zaher, Hend Hussain, Abeer A. Samman and Abeer Zakariyah	25

Association of methionine synthase reductase (MTRR A66G) polymorphism with susceptibility to acute lymphoblastic leukemia by Mashaer Taha Edris, Maye Mohammad Merghani, Shaza Salih Gafar, Ahmed Mohamed Asmali, Elrashed B. Yasin, Raed Alserihi, Heba Alkhatabi, Haitham MH. Qutob, Rowaid Qahwaji, and Elshazali Widaa Ali	26

Safety And Efficacy Of Low-dose Thalidomide In Patients With Transfusion Dependent Thalassemia: A Clinico-hematological Assessment by Muhammad Idrees, Muhammad Tariq Masood Khan, Waleed Bawazir, Mohannad S. Hazzazi, Saeed M. Kabrah, Malik A. Altayar, Soad Al- Jaouni, Majed N. Almashjary, Steve Harakeh and Yasar M Yousafzai	27

Predisposing Factors and Incidence of Venous Thromboembolism among Hospitalized Patients with Sickle Cell Disease by Mohammed S. Ziyadah, Eman M. Mansory, Hatem M. Alahwal, Salem M. Bahashwan, Abdullah T. Almohammadi, Osman O. Radhwi, Talal Alghamdi, Shahida A. Khan, Majed N. Almashjary and Ahmed S. Barefah	28

Cortisone-loaded stearoyl ascorbic acid based nanostructured lipid carriers alleviate inflammatory changes in DSS-induced colitis by Rakesh Kumar Mishra a, Anas Ahmad b, Ajay Kumar a, Aneesh Ali a, Kanika a, Chandrashekhar Jori a, Shams Tabrez c d, Torki A. Zughaibi c d, Majed N. Almashjary d e f, Syed Shadab Raza g, Rehan Khan	29

Mirtazapine attenuated cadmium-induced neuronal intoxication by regulating Nrf2 and NF-κB/TLR4 signals by Saif A. Alharthy,Torki A. Zughaibi,Puneet Vij,Shams Tabrez,Majed N. Almashjary,Sarah Alharthi,Turki Alamri,Badra S. Alghamdi,Steve Harakeh,Sheren A. Azhari,Reem M. Farsi,Hanan S. Althagafy and H. M. Hassanein	30

Fabrication Of A Three-dimensional Bone Marrow Niche-like Acute Myeloid Leukemia Disease Model By An Automated And Controlled Process Using A Robotic Multicellular Bioprinting System by Dana M. Alhattab, Ioannis Isaioglou, Salwa Alshehri, Zainab N. Khan, Hepi H. Susapto, Yanyan Li, Yara Marghani, Arwa A. Alghuneim, Rubén Díaz-rúa, Sherin Abdelrahman, Shuroug Al-bihani, Farid Ahmed, Raed I. Felimban, Heba Alkhatabi, Raed Alserihi, Malak Abedalthagafi, Alshaibani Alfadel, Abdalla Awidi, Adeel Gulzar Chaudhary, Jasmeen Merzaban, And Charlotte A. E. Hauser	31

Inhibitory potential of rutin and rutin nano-crystals against Helicobacter pylori, colon cancer, hemolysis and Butyrylcholinesterase in vitro and in silico by Husam Qanash, Aisha M. H. Al-Rajhi, Majed N. Almashjary, Ammar A. Basabrain, Mohannad S. Hazzazi & Tarek M. Abdelghany	32

Attitude of Previous Blood Donors toward Blood Donation during COVID-19 by Alahwal, Hatem M.1,2; Nour, Yasmin Mohamed Abbas1; Khan, Shahida A.3,4; Barefah, Ahmed S1,2; Bahashwan, Salem M.1,2; Radhwi, Osman O.1,2; Alzahrani, Atheer Mousa Saeed1; Tash, Rawan Azizullah Marouf1; Bajunaid, Weam M1; Alkhaldi, Afaf Bader Radi3; Almohammadi, Abdullah T.1,2	33

Acute Myeloid Leukemia with Acute Spinal Cord Compression as the First Feature by Almohammadi, Abdullah1,2; Bahashwan, Salem1,2; Barefah, Ahmad1,2; AlAhwal, Hatem1,2; Radhwi, Osman1,2; Barefah, Ghaith3; Daous, Yara2,4	34

Anticoagulant prophylaxis in pregnant women with a history of venous thromboembolism: A systematic review and meta-analysis by Eman M. Mansory a b, Lotus Alphonsus c, Janine R. Hutson d, Barbra de Vrijer d, Alejandro Lazo-Langner	35

Antimicrobial, Anticancer, and Antioxidant Activities of Maize and Clover Pollen Grains Extracts: A Comparative Study with Phytochemical Characterizations by Heba Barnawi, Husam Qanash, Abdu Aldarhami, Ghaida Alsaif, Bandar Alharbi, Majed N. Almashjary, Alhomidi Almotiri and Abdulrahman S. Bazaid	36

Antiphospholipid Antibody Testing: An Audit on Testing Practices in a Public Tertiary Care Center by Eman M. Mansory, Hatem M. Alahwal, Salem M. Bahashwan, Osman Radhwi, Abdullah T. Almohammadi, Yassir Daghistani, Jamil Al-Mughales and Ahmed S. Barefah	37

Identification of potential inhibitors targeting Ebola virus VP35 protein: a computational strategy by Yan-kun Chen,Reem M. Gahtani,Mesfer Al Shahrani,Umme Hani,Fahad M. Alshabrmi,Sarfaraz Alam,Hailah M. Almohaimeed,Ammar A. Basabrain and Muhammad Shahab	38

Application of Newly Customized Myeloid NGS Panel in the Diagnosis of Myeloid Malignancies by Alkhatabi HA, Alqahtani W, Alsolami R, Elaimi A , Hazzazi MS , Almashjary MN, Alkhatabi HA, Alghuthami ME, Daous YM, Yasin EB , Barefah A	39

المنشورات العلمية لعام 2022

Implications of SARS-CoV-2 infection on the clinical, hematological,and inflammatory parameters in COVID-19patients:Aretrospective cross-sectional study	1

Impact of COVID-19 on Blood Donation and Supply: A Multicenter Cross-Sectional Study from Saudi Arabia, Nora Y. Hakami ,1Afnan J. Al-Sulami,2Wafaa A. Alhazmi,1Talal H. Qadah,1Waleed M. Bawazir,1,3Abdullah Y. Hamadi,4Amani Y. Owaidah,5Razan A. Alhefzi,6Fawaz Y. Hamdi,7Amr Maqnas,8Ghassab F. Alghassab,9and Maha A. Badawi2,3,10 et al.	2

Immunogenicity of The BNT162b2 COVID-19 mRNA and ChAdOx1 nCoV-19 Vaccines in Patients with Hemoglobinopathies by Osman O. Radhwi , Hamza Jan , Abdullah Waheeb , Sawsan S. Alamri , Hatem M. Alahwal , Iuliana Denetiu , Ashgan Almanzlawey , Adel F. Al-Marzouki , Abdullah T. Almohammadi , Salem M. Bahashwan , Ahmed S. Barefah , Mohamad H. Qari , Adel M. Abuzenadah and Anwar M. Hashem	3

Metabolic Biomarkers in B-Cell Lymphomas for Early Diagnosis and Prediction, as Well as Their Influence on Prognosis and Treatment by Abdullah Alfaifi , Salem Bahashwan , Mohammed Alsaadi , Hafiz Malhan , Aqeel Aqeel , Waiel Al-Kahiry , Hussein Almehdar and Ishtiaq Qadri	4

Enhancing the Antipsychotic Effect of Risperidone by Increasing Its Binding Affinity to Serotonin Receptor via Picric Acid: A Molecular Dynamics Simulation by Majid Alhomrani , Walaa F. Alsanie , Abdulhakeem S. Alamri , Hussain Alyami , Hamza Habeeballah , Heba A. Alkhatabi , Raed I. Felimban , John M. Haynes , Sonam Shakya , Bassem M. Raafat , Moamen S. Refat and Ahmed Gaber	5

TP53 Expression and Mutational Analysis in Hematological Malignancy in Jeddah, Saudi Arabia by Heba Alkhatabi , Elrashed B. Yasin , Zeenat Mirza , Raed Alserihi , Raed Felimban , Aisha Elaimi , Manal Shaabad , Lina Alharbi , Hameeda Ahmed , Abdulrahman M. Alameer , Abdullah Ebraheem Mathkoor and Ahmed Salleh Barefah	6

Deciphering SARS CoV-2-associated pathways from RNA sequencing data of COVID-19-infected A549 cells and potential therapeutics using in silico methods	7

Consumption of Food Components of the Mediterranean Diet Decreases the Risk of Breast Cancer in the Makkah Region, Saudi Arabia: A Case-Control Study Firas S. Azzeh1,2*, Deena M. Hasanain1,3, Alaa H. Qadhi1, Khloud J. Ghafouri1, Wedad F. Azhar1, Mazen M. Ghaith4, Abdullah F. Aldairi4, Hussain A. Almasmoum4, Hamza M. Assaggaf4, Maha H. Alhussain5, Ahmad A. Alghamdi6, Mahmoud M. Habibullah7,8, Waleed M. Bawazir9,10, Sofyan S. Maghaydah2, Maysoun S. Qutob2 and Awfa Y. Alazzeh11	8

Zingiberene exerts chemopreventive activity against 7,12-dimethylbenz(a)anthracene-induced breast cancer in Sprague-Dawley rats Vidya Devanathadesikan Seshadri, Atif Abdulwahab A. Oyouni, Waleed M. Bawazir, Suliman A. Alsagaby, Khalaf F. Alsharif, Ashraf Albrakati, Osama M. Al-Amer	9

Covid-19 Vaccine Perception and hesitancy Among Patients with Sickle Cell Disease in the Western Region of Saudi Arabia	10

Systematic Review and Meta-Analysis of the Susceptibility of ABO Blood Groups to Venous Thromboembolism in Individuals with Factor V Leiden by Waleed M. Bawazir	11

Stachytarpheta cayennensis-mediated copper nanoparticles shows anticancer activity in both in vitro and in vivo models Vidya Devanathadesikan Seshadri, Kavitha Kandasamy, Manal Al Osaimi, Gamal Gabr, Mehnaz Kamal, Mustafa Poyil, Atif Abdulwahab A. Oyouni, Malik A. Altayar, Mohammed M. Jalal, Abdullah M. K. Albloshi, Waleed M. Bawazir & Abubucker Peer Mohideen	12

The Frequencies of ABO and Rh Phenotypes among Male Blood Donors in Northwestern Saudi Arabia Husam Qanash, Jerold C Alcantara, Abdulrahman M Alshammari, Asim Aljuhani, Naif K Binsaleh, Majed N Almashjary, Waleed M Bawazir, Nadi Alshammari, Loai Imam	13

Quality of Systematic Reviews/Meta-Analyses in Coronavirus Disease 2019 and Venous Thromboembolism:An Analysis using a mesurement tool to assess systematic reviews-2	14

Patient Activation Measure amoung transfusion-dependent patients with hemoglobinopaties	15

A Smart Chatbot for Interactive Management in Beta Thalassemia Patients	16

Outcome Prediction of Hematologic Malignancy in Critically Sick People Palanivel Velmurugan ,1Vinayagam Moihanavel,1,2Malik A. Altayar,3Mohammed M. Jalal,3Saeed M. Kabrah,4Husam Qanash,5,6Majed N. Almashjary,7,8Osama M. Alshehri,9and Vijay Singh Kunwar	17

Nrf2/HO-1 Signaling Stimulation through Acetyl-11-Keto-Beta-Boswellic Acid (AKBA) Provides Neuroprotection in Ethidium Bromide-Induced Experimental Model of Multiple Sclerosis by Shubham Upadhayay , Sidharth Mehan , Aradhana Prajapati , Pranshul Sethi , Manisha Suri , Ayat Zawawi , Majed N. Almashjary and Shams Tabrez	18

The Effects of Prenatal Exposure to Pregabalin on the Development of Ventral Midbrain Dopaminergic Neurons by Walaa F. Alsanie , Majid Alhomrani , Ahmed Gaber , Hamza Habeeballah , Heba A. Alkhatabi , Raed I. Felimban , Sherin Abdelrahman , Charlotte A. E. Hauser , Adeel G. Chaudhary , Abdulhakeem S. Alamri , Bassem M. Raafat, Abdulwahab Alamri , Sirajudheen Anwar , Khaled A. Alswat , Yusuf S. Althobaiti and Yousif A. Asiri	19

The Influence of Prenatal Exposure to Quetiapine Fumarate on the Development of Dopaminergic Neurons in the Ventral Midbrain of Mouse Embryos by Walaa F. Alsanie , Sherin Abdelrahman , Majid Alhomrani , Ahmed Gaber , Ebtisam Abdulah Alosimi , Hamza Habeeballah , Heba A. Alkhatabi , Raed I. Felimban , Charlotte A. E. Hauser , Hossam H. Tayeb , Abdulhakeem S. Alamri , Abdulwahab Alamri , Bassem M. Raafat , Khaled A. Alswat , Yusuf S. Althobaiti and Yousif A. Asiri	20

Spectroscopic and Molecular Docking Analysis of π-Acceptor Complexes with the Drug Barbital by Abdulhakeem S. Alamri , Majid Alhomrani , Walaa F. Alsanie , Hussain Alyami , Sonam Shakya , Hamza Habeeballah , Osama Abdulaziz , Abdulwahab Alamri , Heba A. Alkhatabi , Raed I. Felimban , Abdulhameed Abdullah Alhabeeb, Moamen S. Refat and Ahmed Gaber	21

Prenatal Exposure to Gabapentin Alters the Development of Ventral Midbrain Dopaminergic Neurons, Walaa F. Alsanie, Sherin Abdelrahman, Majid Alhomrani, Ahmed Gaber, Hamza Habeeballah, Heba A. Alkhatabi, Raed I. Felimban, Charlotte A. E. Hauser, H. Tayeb, S. Alamri, M. Raafat, Anwar, A. Alswat, S. Althobaiti, and A. Asiri	22

Enhancement of Haloperidol Binding Affinity to Dopamine Receptor via Forming a Charge-Transfer Complex with Picric Acid and 7,7,8,8-Tetracyanoquinodimethane for Improvement of the Antipsychotic Efficacy by Abdulhakeem S. Alamri , Majid Alhomrani , Walaa F. Alsanie , Hussain Alyami , Sonam Shakya , Hamza Habeeballah , Abdulwahab Alamri , Omar Alzahrani , Ahmed S. Alzahrani , Heba A. Alkhatabi , Raed I. Felimban , Abdulhameed Abdullah Alhabeeb , Bassem M. Raafat , Moamen S. Refat and Ahmed Gaber	23

Increasing the Efficacy of Seproxetine as an Antidepressant Using Charge–Transfer Complexes by Walaa F. Alsanie , Abdulhakeem S. Alamri , Hussain Alyami , Majid Alhomrani , Sonam Shakya , Hamza Habeeballah , Heba A. Alkhatabi , Raed I. Felimban , Ahmed S. Alzahrani , Abdulhameed Abdullah Alhabeeb , Bassem M. Raafat , Moamen S. Refat and Ahmed Gaber	24

Multispectral and Molecular Docking Studies Reveal Potential Effectiveness of Antidepressant Fluoxetine by Forming π-Acceptor Complexes by Ahmed Gaber , Walaa F. Alsanie , Majid Alhomrani , Abdulhakeem S. Alamri , Hussain Alyami , Sonam Shakya , Hamza Habeeballah , Heba A. Alkhatabi , Raed I. Felimban , Abdulwahab Alamri , Abdulhameed Abdullah Alhabeeb , Bassem M. Raafat and Moamen S. Refat	25

Attempting to Increase the Effectiveness of the Antidepressant Trazodone Hydrochloride Drug Using π-Acceptors by Walaa F. Alsanie , Majid Alhomrani , Abdulhakeem S. Alamri , Hussain Alyami , Sonam Shakya , Hamza Habeeballah , Heba A. Alkhatabi , Raed I. Felimban , Abdulwahab Alamri , Abdulhameed Abdullah Alhabeeb , Bassem M. Raafat , Moamen S. Refat and Ahmed Gaber	26

A literature perspective on the pharmacological applications of yohimbine Nasimudeen R. Jabir , Chelapram K. Firoz , Torki A. Zughaibi , Mohammed Abdullah Alsaadi , Adel M. Abuzenadah , Ahmed Ibrahim Al-Asmari , Ahdab Alsaieedi , Bakrudeen Ali Ahmed , Arun Kumar Ramu & Shams Tabrez	27

Identification of pathogenic genes associated with CKD: An integrated bioinformatics approach ,Mohd Murshad Ahmed, Zoya Shafat, Safia Tazyeen, Rafat Ali, Majed N. Almashjary, Rajaa Al-Raddadi, Steve Harakeh, Aftab Alam, Shafiul Haque and Romana Ishrat	28

Reticulocyte Hemoglobin-Equivalent Potentially Detects, Diagnoses and Discriminates between Stages of Iron Deficiency with High Sensitivity and Specificity by Majed N. Almashjary , Ahmed S. Barefah , Salem Bahashwan , Ibraheem Ashankyty , Refaat ElFayoumi , Majed Alzahrani , Duaa M. Assaqaf , Raghad S. Aljabri , Amera Y. Aljohani , Rema Muslim , Sara A. Baawad , Waleed M. Bawazir and Saif A. Alharthy	29

Transcriptomic Analysis of Conserved Telomere Maintenance Component 1 (CTC1) and Its Association with Leukemia by Saadiya Zia , Netasha Khan , Komal Tehreem , Nazia Rehman , Rokayya Sami , Roua S. Baty , Faris J. Tayeb , Majed N. Almashjary , Nouf H. Alsubhi , Ghadeer I. Alrefaei and Ramla Shahid	30

Antioxidant, Anticancer, Antibacterial, Antibiofilm Properties and Gas Chromatography and Mass Spectrometry Analysis of Manuka Honey: A Nature’s Bioactive Honey by Abdulrahman S. Bazaid , Abdulwahab Alamri , Majed N. Almashjary , Husam Qanash , Ali A. Almishaal , Junaid Amin , Naif K. Binsaleh , Jamil Kraiem , Abdu Aldarhami and Ahmed Alafnan	31

A potential association between obesity and reduced effectiveness of COVID-19 vaccine-induced neutralizing humoral immunity Arwa A. Faizo, Fadi S. Qashqari, Sherif A. El-Kafrawy, Osamah Barasheed, Majed N. Almashjary, Mohammed Alfelali, Asma A. Bawazir, Boshra M. Albarakati, Soud A. Khayyat, Ahmed M. Hassan, Thamir A. Alandijany, Esam I. Azhar	32

Methylation of the suppressor of Cytokine Signaling 1 Gene (SOCS1) in Philadelphia-negative myeloproliferative neoplasms	33

المنشورات العلمية لعام 2021

Low clinical utility of testing for anti‐platelet factor 4 in asymptomatic individuals after ChAdOx1 nCoV‐19 vaccineز Barefah AS, Radhwi OO, Alamri SS, Alahwal HM, Denetiu I, Almohammadi AT, Bahashwan SM, Qari MH, Algaissi A, Alamer E, Alhazmi A. International Journal of Laboratory Hematology. 2021 Nov 30.	1

Dysregulation of miRNAs in DLBCL: Causative Factor for Pathogenesis, Diagnosis and Prognosis.Alsaadi M, Khan MY, Dalhat MH, Bahashwan S, Khan MU, Albar A, Almehdar H, Qadri I. Diagnostics. 2021 Oct;11(10):1739.	2

Reviewing Publication Discussing the Frequency of ABO and Rhesus-D Blood Groups in Saudi Arabia. Saeed M. Kabrah1*, Arwa F. Flemban2, Asim A. Khogeer3 and Waleed M. Bawazir, JO	3

The distribution of Duffy alleles and genotypes in a Western Saudi cohort.Bawazir WM, Khogeer A, Ashour A, Sabbag M, Alserihi R, Felimban R, Hakami N, Altayar M, Mirza A, Elfayomi R, Shinawi T.	4

Web-based expert system with quick response code for beta-thalassemia management. Banjar HR, Zaher GF, Almutiry HS, Alshamarni AS, Almouhana GI, Alahwal HM, Bahashwan S, Barefah AS, Alnajjar SA, Alharbi HM. Health Informatics Journal. 2021 Feb;27(1)	5

Lack of Antibodies to SARS-CoV-2 among Blood Donors during COVID-19 Lockdown: A Study from Saudi Arabia by Thamir A. Alandijany , Sherif A. El-Kafrawy , Abrar A. Al-Ghamdi , Fadi S. Qashqari , Arwa A. Faizo , Ahmed M. Tolah , Ahmed M. Hassan , Sayed S. Sohrab , Salwa I. Hindawi , Maha A. Badawi and Esam I. Azhar	6

Improving detection rates of suspected acute transfusion reactions through active surveillance. Badawi MA, Saaty R, Altayyari ST, Khalil R, Moria F, Zaher G, Alnajjar S, Hindawi SI. Iraqi Journal of Hematology. 2021 Jul 1;10(2):165.	7

Diagnosis and management of hematological manifestations of gaucher disease: Insights from Saudi Arabia. Owaidah T, Alabbas F, Alhazmi I, Al Saeed H, Balelah S, ElYamany G, Kashari O, Qari M, Saleh M, Roushdy S, ElBagoury M. Journal of Applied Hematology. 2021 Jul 1;12(3):123.	8

Iron Chelation Reduces DNA Damage in Sickle Cell Anemia Rawan S. Al-Khateeb, Hanan S. Althagafy, Mohammad Zaki ElAssouli, Dunya A. Nori, Mohammed AlFattani, Salwa A. Al-Najjar, Turki Al Amri, Anwar M. Hashem, Steve Harakeh and Nawal Helmi	9

الجوائز العلمية

جائزة أفضل عرض ملخص شفهي بعنوان "تجربة مراكز سعودية متعددة في مجال تبادل البلازما العلاجية للمرضى الذين يعانون من فرفرية نقص الصفيحات: دعوة للتسجيل الوطني" من الجمعية السعودية لأمراض الدم , سبتمبر 2023

جائزة ورقة العام من الجمعية السعودية لاضطرابات الدم بعنوان "مناعة لقاحات BNT162b2 Covid-19 mRNA و ChAdOx1 nCoV-19 في المرضى الذين يعانون من اعتلال الهيموغلوبين" – مارس 2022

المركز الثاني في جائزة أفضل ملخص من الجمعية السعودية لاضطرابات الدم بعنوان "فائدة سريرية منخفضة لاختبار العامل المضاد للصفائح الدموية الرابع في الأفراد الذين لا تظهر عليهم أعراض بعد لقاح ChAdOx1 nCoV-19."- مارس 2022

المؤتمرات العلمية

مشاركة بعنوان "تجربة مراكز سعودية متعددة في مجال تبادل البلازما العلاجية للمرضى الذين يعانون من فرفرية نقص الصفيحات: دعوة للتسجيل الوطني" المتحدث د. عثمان رضوي في المؤتمر السعودي السنوي لأمراض الدم , سبتمبر 2023

مشاركة بعنوان "فهم المسار الجزيئي المؤدي إلى مقاومة العلاج في سرطان الدم النخاعي المزمن الإيجابي BCR-ABL", المتحدث د. هبة الخطابي في يوم البحث السنوي, مايو 2022

مشاركة بعنوان "تقييد الحديد الناجم عن تأثير الكبد في نموذج الفأر المعدّل وراثيًا لمرض الخلايا المنجلية", المتحدث د. ماجد المشجري في المؤتمر السعودي السنوي لأمراض الدم 2022 (لقاء افتراضي) , مارس 2022

مشاركة بعنوان "مناعة لقاحات BN't162b2 Covid-19mRNA و ChAdOx1 nCoV-19 في المرضى الذين يعانون من اعتلال الهيموغلوبين", المتحدث د. عثمان رضوي في المؤتمر السعودي السنوي لأمراض الدم 2022 (لقاء افتراضي) , مارس 2022

مشاركة بعنوان "فائدة سريرية منخفضة لاختبار العامل المضاد للصفائح الدموية الرابع في الأفراد الذين لا تظهر عليهم أعراض بعد لقاح ChAdOx1 nCov-19.", المتحدث د. أحمد بارفعه في المؤتمر السعودي السنوي لأمراض الدم 2022 (لقاء افتراضي) , مارس 2022

مشاركة بعنوان "مرض القلعة ", المتحدث د. أحمد بارفعه في المؤتمر السنوي المشترك للجمعية السعودية لزراعة الدم والنخاع العظميSSBMT والجمعية السعودية لأمراض الدم SSH , فبراير 2022

مشاركة بعنوان "التوصية الدولية بشأن تشخيص وعلاج الهيموفيليا المكتسبة ", المتحدث د. عبدالله المحمدي في المؤتمر السنوي المشترك للجمعية السعودية لزراعة الدم والنخاع العظميSSBMT والجمعية السعودية لأمراض الدم SSH , فبراير 2022

مشاركة بعنوان "تضخم الطحال ، من بين الاضطرابات الدموية الشائعة ", المتحدث أ.د. محمد قاري في المؤتمر السنوي المشترك للجمعية السعودية لزراعة الدم والنخاع العظميSSBMT والجمعية السعودية لأمراض الدم SSH , فبراير 2022

مشاركة بعنوان "مقاييس النتائج المُبلغ عنها من قبل المريض في أمراض الدم: ما هي أفضل وسيلة", المتحدث د. منصور رضوي في المؤتمر السنوي المشترك للجمعية السعودية لزراعة الدم والنخاع العظميSSBMT والجمعية السعودية لأمراض الدم SSH , فبراير 2022

Participation with a poster at the 63rd Annual Meeting of the American Society of Hematology (ASH) entitled “A Conceptual Framework for Assessment of Patients Who May Need Red Blood Cell Transfusions” "