KFMRC

kfmrc@kau.edu.sa

(25027 ,61453) 00966-12-695-2000

الأبحاث

المنشورات العلمية

مركز الملك فهد للبحوث الطبية هو مركز أبحاث رائد بنتاج علمي زاخر من عام 1981 م وحتى الان
* لعرض المنشورات العلمية يرجى اختيار سنة النشر

المنشورات العلمية لعام 2023

Modulation of Gut Microbiome Community Mitigates Multiple Sclerosis in a Mouse Model: The Promising Role of Palmaria palmata Alga as a Prebiotic.Yousof, S.M.; Alghamdi, B.S.; Alqurashi, T.; Alam, M.Z.; Tash, R.; Tanvir, I.; Kaddam, L.A. Pharmaceuticals 2023, 16, 1355.
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Effect of Extraction Methods on the Antioxidant Potential and Cytotoxicity of the Combined Ethanolic Extracts of Daucus carota L., Beta vulgaris L., Phyllanthus emblica L. and Lycopersicon esculentum against Gastric Adenocarcinoma Cells by Mahima Chauhan 1,Vandana Garg 1,Ghazala Zia 1,Rohit Dutt 2ORCID,Badrah S. Alghamdi 3,4,Ayat Zawawi 5,6,Ghulam Md. Ashraf 7,*ORCID andAisha Farhana med A. Alfaleh,c,g Shaimaa M. Badr-Eldin,c,h Hibah M. Aldawsari,c,d Mohammed A. S. Abourehab,i,j Hani Z. Asfour,k Shadi A. Zakai,k Mohammad W. Alrabia,k Aya A. Negm,l Mohamed A. El-Moselhy,m,n Sara S. Sharkawi, Waleed Y. Rizgc 2



Gap between recognition and response to stroke scenarios among Saudi population: Cross-sectional survey study. Al-Hayani MM, Aljudibi RA, Alatawi Y, Alghamdi BS.J Stroke Cerebrovasc Dis. 2023 Sep;32(9):107237. doi: 10.1016/j.jstrokecerebrovasdis.2023.107237. Epub 2023 Jul 22. PMID: 37487319 3



Computational insight into the binding of bryostatin 1 with ferritin: implication of natural compounds in Alzheimer's disease therapeutics. Shahwan M, Alhumaydhi FA, Sharaf SE, Alghamdi BS, Baeesa S, Tayeb HO, Ashraf GM, Shamsi A.J Biomol Struct Dyn. 2023 Jul-Aug;41(12):5635-5645. doi: 10.1080/07391102.2022.2092552. Epub 2022 Jul 5. PMID: 35787781 4



Neurodegeneration and inflammation crosstalk: Therapeutic targets and perspectives. Mohamed W, Kumar J, Alghamdi BS, Soliman AH, Toshihide Y.IBRO Neurosci Rep. 2022 Dec 16;14:95-110. doi: 10.1016/j.ibneur.2022.12.003. PMID: 37388502; PMCID: PMC10300452
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Therapeutic potential of lipid nanosystems for the treatment of Parkinson's disease. Preetam S, Jonnalagadda S, Kumar L, Rath R, Chattopadhyay S, Alghamdi BS, Abuzenadah AM, Jha NK, Gautam A, Malik S, Ashraf GM. Ageing Res Rev. 2023 Aug;89:101965. doi: 10.1016/j.arr.2023.101965. Epub 2023 May 31. PMID: 37268112.
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Mitochondrial Medicine: A Promising Therapeutic Option Against Various Neurodegenerative Disorders. Almikhlafi MA, Karami MM, Jana A, Alqurashi TM, Majrashi M, Alghamdi BS, Ashraf GM.Curr Neuropharmacol. 2023;21(5):1165-1183. doi: 10.2174/1570159X20666220830112408. PMID: 36043795; PMCID: PMC10286591
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Exploration of acute and chronic anti-inflammatory potential of Quercus leucotrichophora A. Saleem A, Hameed I, Akhtar MF, Ashraf GM, Alghamdi BS, Rahman MH, Almashjary MN.Camus extracts in Wistar rats: A mechanistic insight. Front Pharmacol. 2023 Apr 11;14:1002999. doi: 10.3389/fphar.2023.1002999. PMID: 37113751; PMCID: PMC10126476
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Mitochondrial Medicine for Neurological Disorders. Sahab Uddin M, Alghamdi BS, Ashraf GM. Curr Neuropharmacol. 2023;21(5):1024-1025. doi: 10.2174/1570159X2105230320095644. PMID: 37203188; PMCID: PMC10286594. 9
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Emerging Promise of Therapeutic Approaches Targeting Mitochondria in Neurodegenerative Disorders. Rahman MM, Tumpa MAA, Rahaman MS, Islam F, Sutradhar PR, Ahmed M, Alghamdi BS, Hafeez A, Alexiou A, Perveen A, Ashraf GM.Curr Neuropharmacol. 2023;21(5):1081-1099. doi: 10.2174/1570159X21666230316150559. PMID: 36927428; PMCID: PMC10286587 10



Knowledge, Attitude, and Practice Regarding Burns Prevention and Burn First Aid Among Medical Students of King Abdulaziz University, Saudi Arabia; LS Alghamdi, AM Alahmari, HM Alshaibani, MA Alem, NM Aloufi. International Journal of Surgery and Medicine 9 (2), 44-44 11



Depression, anxiety and stress in Saudi migraine patients using DASS-21: local population-based cross-sectional survey. Al-Hayani M, AboTaleb H, Bazi A, Alghamdi B. Int J Neurosci. 2023 Mar;133(3):248-256. doi: 10.1080/00207454.2021.1909011. Epub 2021 Apr 14. PMID: 33843418. 12 12



Editorial: Translational neuroscience and reverse translational neuroscience: What's giving us hope? Front Neurosci. Mohamed WMY, Alghamdi BS, Alexiou A.2023 Feb 22;17:1149819. doi: 10.3389/fnins.2023.1149819. PMID: 36908775; PMCID: PMC9992888. 13 13



Potential Regulation of miRNA-29 and miRNA-9 by Estrogens in Neurodegenerative Disorders: An Insightful Perspective. Ebada, M.A.; Mostafa, A.; Gadallah, A.-H.A.; Alkanj, S.; Alghamdi, B.S.; Ashraf, G.M.; Abuzenadah, A.M.; Alserihi, R.F.; Wadaa-Allah, A.; Salama, M.Brain Sci. 2023, 13, 243 14



Recent Updates on Corticosteroid-Induced Neuropsychiatric Disorders and Theranostic Advancements through Gene Editing Tools Manisha Singh 1, Vinayak Agarwal 1, Divya Jindal 1, Pranav Pancham 1, Shriya Agarwal 2, Shalini Mani 1, Raj Kumar Tiwari 3, Koushik Das 3, Badrah S Alghamdi 4 5, Tukri S Abujamel 6 7, Ghulam Md Ashraf 5 8, Saurabh Kumar Jha 9 10 11 15



Therapeutic effect of combination vitamin D3 and siponimod on remyelination and modulate microglia activation in cuprizone mouse model of multiple sclerosis. Al-Otaibi, K. M., Alghamdi, B. S., Al-Ghamdi, M. A., Mansouri, R. A., Ashraf, G. M., & Omar, U. M. (2023). Frontiers in behavioral neuroscience, 16, 1068736 16



Chapter 35 - Role of mediterranean diet in Parkinson's disease,; Editor(s): Colin R. Martin, Vinood B. Patel, Victor R. Preedy,; Diet and Nutrition in Neurological Disorders,; ohannad A. Almikhlafi, Badrah Alghamdi, Ghulam Md Ashraf; Academic Press, 2023, Pages 649-665, ISBN 9780323898348 17



Anti sickling effect of Senna alexandrina, Aerva javanica , and Ficus palmata extracts on sickle cell disorder Zahraa M Al Yousef Elaf A Alaswad M‑Zaki M ElAssouli Dunya A Nori Faten Z Filimban Hani Choudhry Mohammad Z Alam Hadeel Al Sadoun Nawal MW Helmi 18



A review on plant-based remedies for the treatment of multiple sclerosisUn aperçu sur les remèdes à base de plantes pour le traitement de la sclérose en plaques Author links open overlay panelMohammad Zubair Alam 19



FGF12 copy number variant associated with epileptic encephalopathy Anna Abraham, Keri Ramsey, Newell Belnap, Szabolcs Szelinger, Wayne Jepsen, Chris Balak, Meredith Sanchez-Castillo, Marcus Naymik, Anna Bonfitto, Sampathkumar Rangasamy, Semyon Kruglyak, Matthew Huentelman, Vinodh Narayanan 20



Targeting Kaposi’s sarcoma associated herpesvirus encoded protease (ORF17) by a lysophosphatidic acid molecule for treating KSHV associated diseases ,Misbahuddin M Rafeeq 1, Hamed Habib 2 ,F. Nahhas3,Najat Binothman 4 ,Majidah Aljadani4 ,Jawaher Almulhim5 ,Ziaullah M Sain6 ,Mohammad Zubair Alam7,8 ,Norah A Alturki 9 ,Qamre Alam 10 ,Manish Manish 11 ,Rajnish Kumar Singh 21



Evaluating Prophylactic And Therapeutic Efficacy Of Vanillic Acid On Neurodegenerative Disorders: A Narrative Review, Rasha M. Alderbi1 , Mohammad Z. Alam2 , Ulfat M. Omar3 , Badrah S. Alghamdi4 , Faisal S. Al-Shehri5 , Maryam A. Al-Ghamdi6 22



Mirtazapine attenuated cadmium-induced neuronal intoxication by regulating Nrf2 and NF-κB/TLR4 signals.Alharthy, S. A., Zughaibi, T. A., Vij, P., Tabrez, S., Almashjary, M. N., Alharthi, S., Alamri, T., Alghamdi, B. S., Harakeh, S., Azhari, S. A., Farsi, R. M., Althagafy, H. S., & Hassanein, E. H. M. (2023). Toxicology mechanisms and methods, 33(8), 675–687 23



Comprehensive mapping of mutations in TDP-43 and α-Synuclein that affect stability and binding , Sultan H. Alamri,Shafiul Haque,Badra S. Alghamdi,Haythum O. Tayeb,Shereen Azhari,Reem M. Farsi,Abear Elmokadem,Turki A. Alamri,Steve Harakeh,Amresh PrakashORCID Icon &Vijay Kumar 24



Fabrication, assessment, and optimization of alendronate sodium nanoemulsion-based injectable in-situ gel formulation for management of osteoporosis By Wesam H. Abdulaal,Khaled M. HosnyORCID Icon,Nabil A. AlhakamyORCID Icon,Rana B. Bakhaidar,Yasir Almuhanna,Fahad Y. Sabei,Mohammed Alissa,Mohammed Majrashi,Jawaher Abdullah Alamoudi,Mohannad S. Hazzazi,Ayman Jafer &Rasha A. KhallafORCID Icon 25



Phytochemical Characterization and Efficacy of Artemisia judaica Extract Loaded Chitosan Nanoparticles as Inhibitors of Cancer Proliferation and Microbial Growth By by Husam Qanash, Abdulrahman S. Bazaid, Abdu Aldarhami, Bandar Alharbi, Majed N. Almashjary, Mohannad S. Hazzazi, Hashim R. Felemban and Tarek M. Abdelghany 26



Analysis of NPM1 and FLT3 Mutations in Patients with Acute Myeloid Leukemia in Jeddah, Saudi Arabia: A Pilot Study By Raed Alserihi, Hameeda Ahmad, Heba Alkhatabi and Talal Qadah 27



Enhanced Solubility and Biological Activity of Dexibuprofen-Loaded Silica-Based Ternary Solid Dispersions by Muhammad Asim, Marriam Nazir, Zunera Chauhdary, Muhammad Irfan, Syed Haroon Khalid, Sajid Asghar, Usra, Raed I. Felimban, Mohammed A Majrashi, Mohannad S. Hazzazi, Mohammed Alissa, Safa H Qahl, Ghulam Hussain, Azhar Rasul, Shahzad Ali Shahid Chatha and Ikram Ullah Khan 28



Evaluation of Antidiabetic, Antioxidant and Anti-Hyperlipidemic Effects of Solanum indicum Fruit Extract in Streptozotocin-Induced Diabetic Rats by Manoj M. Gadewar, Prashanth G K, Prabhu Chandra Mishra, Ghulam Md Ashraf, Majed N. Almashjary, Steve Harakeh, Vijay Upadhye, Abhijit Dey, Pallavi Singh, Niraj Kumar Jha and Saurabh Kumar Jha 5 29



Potential Regulation of miRNA-29 and miRNA-9 by Estrogens in Neurodegenerative Disorders: An Insightful Perspective by Mahmoud A. Ebada, Abdalrhman Mostafa, Al-Hussein A. Gadallah, Souad Alkanj, Badrah S. Alghamdi, Ghulam Md Ashraf, Adel M. Abuzenadah, Raed F. Alserihi, Ahmed Wadaa-Allah and Mohamed Salama 30



Lack of Evidence on Association between Iron Deficiency and COVID-19 Vaccine-Induced Neutralizing Humoral Immunity by Arwa A. Faizo, Asma A. Bawazir, Majed N. Almashjary, Ahmed M. Hassan, Fadi S. Qashqari, Ahmed S. Barefah, Sherif A. El-Kafrawy, Thamir A. Alandijany and Esam I. Azhar 31



Impact of COVID-19 Pandemic on Treatment Decisions of Patients Treated by Hematologists in Saudi Arabia by SalemM Bahashwan, Hatem Alahwal, AbdullahT Almohammadi, Osman Radhwi, ShahidaA Khan and Ahmed Barefah 32



Metabolomics: A New Era in the Diagnosis or Prognosis of B-Cell Non-Hodgkin’s Lymphoma by Abdullah Alfaifi, Mohammed Y. Refai, Mohammed Alsaadi, Salem Bahashwan, Hafiz Malhan, Waiel Al-Kahiry, Enas Dammag, Ageel Ageel, Amjed Mahzary, Raed Albiheyri, Hussein Almehdar and Ishtiaq Qadri 33



Incidence and Risk Factors of Infections Among Diffuse Large B-cell Lymphoma and Classical Hodgkin’s Lymphoma Patients in a Tertiary Care Center in Saudi Arabia: A Retrospective Cohort Study by Rakan H. Alelyani, Ali H. Alghamdi, Thamer A. Almughamisi, Abdulrahman M. Alshareef, Abdulaziz N. Kadasa, Amir M. Alrajhi, Abdullah K. Alburayk, Ahmed S. Barefah, Osman O. Radhwi, Abdullah T. Almohammadi, Salem M. Bahashawan, Hatem M. AlAhwal 34



The Influence of Prenatal Exposure to Methamphetamine on the Development of Dopaminergic Neurons in the Ventral Midbrain by Walaa F. Alsanie, Sherin Abdelrahman, Raed I. Felimban, Heba A. Alkhatabi, Ahmed Gaber, Ebtisam Abdulah Alosimi, Majid Alhomrani, Hamza Habeeballah, Charlotte A. E. Hauser, Abdulhakeem S. Alamri, Aiysha Althobaiti, Abdulaziz Alsharif, Ahmed S. Alzahrani, Mohammad S. Al-Ghamdi, Bassem M. Raafat, Khaled A. Alswat, Yusuf S. Althobaiti and Yousif A. Asiri 35



Anticancer Effects of Honey Varieties on Human Cells by Studying Some Physical Parameters, Hydrogen Peroxide Content, Catalase, Glucose Oxidase, and Microbial Activities by Al-Eisa, Rasha A. 1 ; Ashour, Amal Adnan 2 ; Helal, Mahmoud 3 ; Aljahani, Amani H. 4 ; Kadi, Roqayah H. 5 ; Hazzazi, Mohannad S. 6 ; Sami, Rokayya 7 ; 36



Outcomes of Cholelithiasis Among Patients With Sickle Cell Disease: A Tertiary Care Center Experience by Bushra Almalki, Sultan Banser, Banan Alghamdi, Majed Almalki, Adel Al-Marzouki, Mohammed Alharthi and Osman Radhwi 37



Insights from the molecular docking analysis of EGFR antagonists by Mohammad Azhar Kamal1, Hanadi M Baeissa2, Israa J. Hakeem2, Reem S Alazragi2, Mohannad S. Hazzazi3,4, Tahani Bakhsh5, Akhmed Aslam6, Bassem Refaat6, Elshiekh B. Khidir6, Kadhem Juma Alkhenaizi7 & Qamre Alam7* 38



Outcomes of therapeutic plasma exchange A 15-year tertiary center experience by Hindawi, Salwa1,2,3; Radhwi, Osman1,2,; Badawi, Maha1,2,3; Rajab, Hanaa4; Al Mansouri, Fatma5; Alzahrani, Ali6; Bukhari, Hussam7; Gholam, Kholoud3; Almalki, Ahmad3; Awadh, Abdulaziz3; Yagoub, Ismat Khalil3; Zaher, Galila1,2, 39



Exploration of acute and chronic anti-inflammatory potential of Quercus leucotrichophora A. Camus extracts in Wistar rats: A mechanistic insight by Ammara Saleem, Izza Hameed, Muhammad Furqan Akhtar, Ghulam Md Ashraf, Badrah S. Alghamdi, Md. Habibur Rahman and Majed N. Almashjary 40



Blastocystis sp.—An emerging cause of diarrhea post stem cell transplantation by Osman Radhwi, Abdullah Almohammadi, Adel Almarzouki, Ahmed Barefah, Salem Bahashwan, Hatem Alahwal 41



Increased inflammatory cytokines and oxidative stress enhanced antibody production in breast and prostate cancer patients with COVID-19 related depression by Naif K. Binsaleh1, Subuhi Sherwani, Reem Eltayeb, Husam Qanash, Abdulrahman S. Bazaid, Maryam Althobiti, Mohannad S. Hazzazi and Saravanan Rajendrasozhan 42



Is a Higher Body Mass Index a Risk Factor for Developing Antiphospholipid Antibody Syndrome? by Eman M. Mansory, Atheer M. Badawi, Renad Rajab, Asma Abdullah, Mudhawi Alhiniah, Rakan H. Alelyani, Jamil Al-Mughales, Hatem M. AlAhwal and Ahmed S. Barefah 43



A Saudi multicenter experience on therapeutic plasma exchange for patients with thrombotic thrombocytopenic purpura: A call for national registry by Osman Radhwi MD, Maha A. Badawi MD, Adel Almarzouki MD, Fakhr Al-Ayoubi PhD, Ghada ElGohary MD, Kazi Nur Asfina MD, Abdulrahim Mohammed Basendwah MD, Iman Ayed Alhazmi MD, Eiman A. Almahasnah MD, Ahmed AlBahrani MD, Abdulrahman Al Raizah MD, Ayel Yahya MD, Khadeja Alshahrani MD, Salwa Hindawi MD 44



Transplacental Transfer of SARS-CoV-2 Receptor-Binding Domain IgG Antibodies from Mothers to Neonates in a Cohort of Pakistani Unvaccinated Mothers by Steve Harakeh, Ihsan Alam Khan, Gulab Fatima Rani, Muhammad Ibrahim, Aysha Sarwar Khan , Mohammed Almuhayawi , Rajaa Al-Raddadi, Addisu D. Teklemariam, Mohannad S. Hazzazi, Waleed M. Bawazir, Hanouf A. Niyazi, Turki Alamri , Hatoon A. Niyazi and Yasar Mehmood Yousafzai 45



Immunoprofiling of cytokines, chemokines, and growth factors in female patients with systemic lupus erythematosus– a pilot study by Laila A. Damiati, Iuliana Denetiu, Sami Bahlas, Samar Damiati & Peter Natesan Pushparaj 46



Anti-Helicobacter pylori, Antioxidant, Antidiabetic, and Anti-Alzheimer’s Activities of Laurel Leaf Extract Treated by Moist Heat and Molecular Docking of Its Flavonoid Constituent, Naringenin, against Acetylcholinesterase and Butyrylcholinesterase by Aisha M. H. Al-Rajhi 1,Husam Qanash 2ORCID,Majed N. Almashjary 3,4ORCID,Mohannad S. Hazzazi 3,4ORCID,Hashim R. Felemban 3,5 andTarek M. Abdelghany 47



Promoter Methylation-Regulated Differentially Expressed Genes in Breast Cancer by Sindi S, Hamdi N, Hassan S, Ganash M , Alharbi M, Alburae N, Azhari S, Alkhayyat S, Linjawi A, Alkhatabi H, Elaimi A , Alrefaei G, Alsubhi N, Alrafiah A , Alhazmi S 48



Association of Genetic Variant FVIII Gene and Factor VIII: A Pilot Study Among Hemophilia A Female Relatives in Saudi Arabia by Abdullah T. Almohammadi, Osman Radhwi, Hatem AlAhwal, Ahmed Barefah, Salem Bahashwan, Ibraheem M. Ashankyty, Majed Almashjari, Rawan Ayaz, Adel Al-Marzouki, Galila F. Zaher, Hend Hussain, Abeer A. Samman and Abeer Zakariyah 49



Association of methionine synthase reductase (MTRR A66G) polymorphism with susceptibility to acute lymphoblastic leukemia by Mashaer Taha Edris, Maye Mohammad Merghani, Shaza Salih Gafar, Ahmed Mohamed Asmali, Elrashed B. Yasin, Raed Alserihi, Heba Alkhatabi, Haitham MH. Qutob, Rowaid Qahwaji, and Elshazali Widaa Ali 50



Safety And Efficacy Of Low-dose Thalidomide In Patients With Transfusion Dependent Thalassemia: A Clinico-hematological Assessment by Muhammad Idrees, Muhammad Tariq Masood Khan, Waleed Bawazir, Mohannad S. Hazzazi, Saeed M. Kabrah, Malik A. Altayar, Soad Al- Jaouni, Majed N. Almashjary, Steve Harakeh and Yasar M Yousafzai 51



Predisposing Factors and Incidence of Venous Thromboembolism among Hospitalized Patients with Sickle Cell Disease by Mohammed S. Ziyadah, Eman M. Mansory, Hatem M. Alahwal, Salem M. Bahashwan, Abdullah T. Almohammadi, Osman O. Radhwi, Talal Alghamdi, Shahida A. Khan, Majed N. Almashjary and Ahmed S. Barefah 52



Cortisone-loaded stearoyl ascorbic acid based nanostructured lipid carriers alleviate inflammatory changes in DSS-induced colitis by Rakesh Kumar Mishra a, Anas Ahmad b, Ajay Kumar a, Aneesh Ali a, Kanika a, Chandrashekhar Jori a, Shams Tabrez c d, Torki A. Zughaibi c d, Majed N. Almashjary d e f, Syed Shadab Raza g, Rehan Khan 53



Mirtazapine attenuated cadmium-induced neuronal intoxication by regulating Nrf2 and NF-κB/TLR4 signals by Saif A. Alharthy,Torki A. Zughaibi,Puneet Vij,Shams Tabrez,Majed N. Almashjary,Sarah Alharthi,Turki Alamri,Badra S. Alghamdi,Steve Harakeh,Sheren A. Azhari,Reem M. Farsi,Hanan S. Althagafy and H. M. Hassanein 54



Fabrication Of A Three-dimensional Bone Marrow Niche-like Acute Myeloid Leukemia Disease Model By An Automated And Controlled Process Using A Robotic Multicellular Bioprinting System by Dana M. Alhattab, Ioannis Isaioglou, Salwa Alshehri, Zainab N. Khan, Hepi H. Susapto, Yanyan Li, Yara Marghani, Arwa A. Alghuneim, Rubén Díaz-rúa, Sherin Abdelrahman, Shuroug Al-bihani, Farid Ahmed, Raed I. Felimban, Heba Alkhatabi, Raed Alserihi, Malak Abedalthagafi, Alshaibani Alfadel, Abdalla Awidi, Adeel Gulzar Chaudhary, Jasmeen Merzaban, And Charlotte A. E. Hauser 55



Inhibitory potential of rutin and rutin nano-crystals against Helicobacter pylori, colon cancer, hemolysis and Butyrylcholinesterase in vitro and in silico by Husam Qanash, Aisha M. H. Al-Rajhi, Majed N. Almashjary, Ammar A. Basabrain, Mohannad S. Hazzazi & Tarek M. Abdelghany 56



Attitude of Previous Blood Donors toward Blood Donation during COVID-19 by Alahwal, Hatem M.1,2; Nour, Yasmin Mohamed Abbas1; Khan, Shahida A.3,4; Barefah, Ahmed S1,2; Bahashwan, Salem M.1,2; Radhwi, Osman O.1,2; Alzahrani, Atheer Mousa Saeed1; Tash, Rawan Azizullah Marouf1; Bajunaid, Weam M1; Alkhaldi, Afaf Bader Radi3; Almohammadi, Abdullah T.1,2 57



Acute Myeloid Leukemia with Acute Spinal Cord Compression as the First Feature by Almohammadi, Abdullah1,2; Bahashwan, Salem1,2; Barefah, Ahmad1,2; AlAhwal, Hatem1,2; Radhwi, Osman1,2; Barefah, Ghaith3; Daous, Yara2,4 58



Anticoagulant prophylaxis in pregnant women with a history of venous thromboembolism: A systematic review and meta-analysis by Eman M. Mansory a b, Lotus Alphonsus c, Janine R. Hutson d, Barbra de Vrijer d, Alejandro Lazo-Langner 59



Antimicrobial, Anticancer, and Antioxidant Activities of Maize and Clover Pollen Grains Extracts: A Comparative Study with Phytochemical Characterizations by Heba Barnawi, Husam Qanash, Abdu Aldarhami, Ghaida Alsaif, Bandar Alharbi, Majed N. Almashjary, Alhomidi Almotiri and Abdulrahman S. Bazaid 60



Antiphospholipid Antibody Testing: An Audit on Testing Practices in a Public Tertiary Care Center by Eman M. Mansory, Hatem M. Alahwal, Salem M. Bahashwan, Osman Radhwi, Abdullah T. Almohammadi, Yassir Daghistani, Jamil Al-Mughales and Ahmed S. Barefah 61



Identification of potential inhibitors targeting Ebola virus VP35 protein: a computational strategy by Yan-kun Chen,Reem M. Gahtani,Mesfer Al Shahrani,Umme Hani,Fahad M. Alshabrmi,Sarfaraz Alam,Hailah M. Almohaimeed,Ammar A. Basabrain and Muhammad Shahab 62



Application of Newly Customized Myeloid NGS Panel in the Diagnosis of Myeloid Malignancies by Alkhatabi HA, Alqahtani W, Alsolami R, Elaimi A , Hazzazi MS , Almashjary MN, Alkhatabi HA, Alghuthami ME, Daous YM, Yasin EB , Barefah A 63



Modulation of the Tumor Microenvironment by Ellagic Acid in Rat Model for Hepatocellular Carcinoma: A Potential Target against Hepatic Cancer Stem Cells, Wafaa S. Ramadan, Saleh Alkarim, Mohammed Moulay, Ghadeer Alrefeai, Fatma Alkudsy, Khalid Rehman Hakeem and Ashwaq Iskande, Cancers, MDPI 64



Yield and Composition Variations of the Milk from Different Camel Breeds in Saudi Arabia, Amr A. El-Hanafy, Yasser M. Saad, Saleh A. Alkarim, Hussein A. Almehdar, Fuad M. Alzahrani, Mohammed A. Almatry, Vladimir N. Uversky and Elrashdy M. Redwan, SCi, MDPI 65



Computational Molecular Docking and Simulation-Based Assessment of Anti-Inflammatory Properties of Nyctanthes arbor-tristis Linn Phytochemicals by Varish Ahmad , Mohammad Imran Khan , Qazi Mohammad Sajid Jamal , Faisal A. Alzahrani and Raed Albiheyri, MDPI 66



25 (S)-Hydroxycholesterol acts as a possible dual enzymatic inhibitor of SARS-CoV-2 Mpro and RdRp–: an insight from molecular docking and dynamics simulation approaches Faisal A. Alzahrani , Saleh A. Alkarim , Yousef M. Hawsawi , Wesam H. Abdulaal , Raed Albiheyri , Bassem Kurdi, Journal of Biomolecular Structure and Dynamics 65



Plant-Derived Extracellular Vesicles and Their Exciting Potential as the Future of Next-Generation Drug Delivery by Faisal A. Alzahrani, Mohammad Imran Khan , Nader Kameli, Elham Alsahafi and Yasir Mohamed Riza , MDPI 68



Recognition of Differentially Expressed Molecular Signatures and Pathways Associated with COVID-19 Poor Prognosis in Glioblastoma Patients by Faisal A. Alzahrani, Mohd Faheem Khan and Varish Ahmad, MDPI 69



Exosomes from foetal tissue-derived mesenchymal stem cells as a novel product for therapeutic application by Alrefaei Ghadeer 70



Cinnamon and ginger extracts attenuate diabetes-induced inflammatory testicular injury in rats and modulating SIRT1 expression by Ghadeer I. Alrefaei, Hailah M. Almohaimeed, Sami A. Algaidi, Mohammed Saad Almuhayawi, Fatma Mohamed AbdAllah, Nouf S. Al-Abbas, Nehad A. Shaer, Zuhair M. Mohammedsaleh, Fayez M Saleh and Nasra Ayuob 71



Promoter Methylation-Regulated Differentially Expressed Genes in Breast Cancer by Samar Sindi, Norah Hamdi, Sabah Hassan, Magdah Ganash, Mona Alharbi,Najla Alburae, Sheren Azhari, Shadi Alkhayyat, Ayman Linjawi, Heba Alkhatabi, Aisha Elaimi, Ghadeer Alrefaei, Nouf Alsubhi, Aziza Alrafiah, and Safiah Alhazmi 72



Identification of novel interacts partners of ADAR1 enzyme mediating the oncogenic process in aggressive breast cancer by Najat Binothman, Majidah Aljadani, Bandar Alghanem, Mohammed Y. Refai, Mamoon Rashid, Abeer Al Tuwaijri, Nouf H. Alsubhi, Ghadeer I. Alrefaei, Muhammad Yasir Khan, Sultan N. Sonbul, Fadwa Aljoud, Sultan Alhayyani, Rwaa H. Abdulal, Magdah Ganash and Anwar M. Hashem 73



Effect of Co-culturing both placenta-derived mesenchymal stem cells and their condition medium in the cancer cell (HepG2) migration, damage through apoptosis and cell cycle arrest by Opo, FADM et al 74



Nanoformulated 3'-diindolylmethane modulates apoptosis, migration, and angiogenesis in breast cancer cells by Harakeh S, Akefe IO, Saber SH, Alamri T, Al-Raddadi R, Al-Jaouni S, Tashkandi H, Qari M, Moulay M, Aldahlawi A, Abd Elmageed ZY, Mousa S. Heliyon. 2023 Dec 10;10(1):e23553. doi: 10.1016/j.heliyon.2023.e23553. PMID: 38187226; 75



Identification of natural antiviral drug candidates against Tilapia Lake Virus: Computational drug design approaches. by Moulay et al. : PLOS ONE .2023. https://doi.org/10.1371/journal.pone.0287944 76



Bacterial Assessment and Isolation of Antibiotic Resistant Bacteria from the Indian Major Carp, Labeo rohita. by Md.ShemulMiana, et al, Volume 22, Issue 6, Page 34-45, 2023; Article no.AJFAR.96839ISSN: 2582-3760 77



Apoptosis induction in human hepatoma cell line HepG2 cells by trans- Anethole via activation of mitochondria-mediated apoptotic pathways. .Harakeh S, Al-Raddadi R, Alamri T, Al-Jaouni S, Qari M, Qari Y, Kumar A, Tashkandi HM, Moulay M, Aldahlawi AM, Slama P, Haque S. ,Biomed Pharmacother. 2023 Sep;165:115236. doi: 10.1016/j.biopha.2023.115236. Epub 2023 Jul 31. PMID: 37531780. 78



Analysis of some flavonoids for inhibitory mechanism against cancer target phosphatidylinositol 3-kinase (PI3K) using computational tool. by Suhail M, Alzahrani WM, Shakil S, Tarique M, Tabrez S, Zughaibi TA, Rehan M. (2023)Frontiers in Pharmacology, 14:1236173 ,Safiah Alhazmi 79



Targeting a transcription factor NF-κB by green tea catechins using in silico and in vitro studies in pancreatic cancer. by Suhail M*, Rehan M, Tarique M, Tabrez S, Husain A and Zughaibi TA (2023). Frontiers in Nutrition. 9:1078642. ,Safiah Alhazmi 80



Association of interleukin-18 polymorphism with comorbid conditions of cardiovascular disease. by Tabrez S, Jabir NR, Zughaibi TA and Suhail M (2023). Journal of King Saud University-Science 2023,35(1):102440. 81



Differential expression of programmed death 1 (PD-1) on various immune cells and its role in human leprosy. by Tarique M, Naz H, Suhail M, Turan A, Saini C, Muhammad N, Shankar H, Zughaibi TA, Khan TH, Kanna N and Sharma A (2023). Frontiers in Immunology. 14:1138145. 82



Synergistic inhibition of glioblastoma multiforme through an in-silico analysis of luteolin and ferulic acid derived from angelica sinensis and cannabis sativa: Advancements in computational therapeutics. by Suhail M*, Tarique M, Tabrez S, Zughaibi TA and Rehan M (2023). PLOS ONE. 10.1371/journal.pone.0293666 83



Husk-like zinc oxide nanoparticles induce apoptosis through ROS generation in epidermoid carcinoma cells: Effect of incubation period on sol-gel synthesis and anti-cancerous properties. by Alhoqail WA, Alothaim AS, Suhail M, Iqbal D, Kamal M, and Jamal A (2023). Biomedicines. 2023;11(2):320 84



Interlinking of diabetes mellitus and cancer: An overview. by Ahmad I, Suhail M, Ahmad A, Alhosin M and Tabrez S (2023). Cell Biochemistry and Function. 2023; 41(5):506-516. 85



Bioinformatics data investigation of microarray and RNA seq datasets to classify rare biomarkers for cervical cancerby Zughaibi TA, Suhail M, Al-Asmari AI, Rehman MT, AlAjmi MF and Tabrez S (2023).Pharmaceuticals 86



Oral delivery of aescin nanodrug formulated gelatin nanoparticles ameliorates carbontetrachloride-induced hepatotoxicity in wistar rats. by Ansari MM, Jori C, Tabrez S, Zughaibi TA, Suhail M, Raza SS and Khan R (2023) Food and Chemical Toxicology 87



Anticancer potential activity of Cu4O3 NPs against human ovarian teratocarcinoma: An in-vitro study. by Jabir NR, Suhail M, Khan MS, Arshad M and Tabrez S (2023).Applied Biochemistry and Biotechnology 88



Investigating microarray and RNA seq datasets to classify rare biomarkers for cervical cancer. by Zughaibi TA, Suhail M, Abdullah EM, Saud AM, Tabish RM, AlAjmi MF, Khan MS and Tabrez S (2023).Royal Society Open Science [IF 3.653] (Manuscript under review) 89



Cortisone-loaded stearoyl ascorbic acid based nanostructured lipid carriers alleviate inflammatory changes in DSS-induced colitis. by Mishra RK, Ahmad A, Kumar A, Ali A, Bhutani K, Jori C, Tabrez S, Zughaibi TA, Almashjary MN, Khan R. (2023) Biomaterials Advances, 148: 213383. 90



Nanomedicine based immunotherapy for Alzheimer’s Disease.by Hoque M, Samanta A, Alam SSM, Zughaibi TA, Kamal MA, Tabrez S*. (2023) Neuroscience and Biobehavioral Reviews, 144: 104973 91



Renal mitochondrial restoration by gymnemic acid in gentamicin-mediated experimental nephrotoxicity: Evidence from serum, kidney, and histopathological alterations.by Gumbar S, Bhardwaj S, Mehan S, Khan Z, Narula AS, Kalfin R, Tabrez S*, Zughaibi TA, Wasi S. (2023) Frontiers in Pharmacology, 14: 1218506 92



Metabolomics analysis as a tool to measure cobalt neurotoxicity: An in-vitro validation. by OAlanazi IMM, Alzahrani AR, Zughaibi TA, Al-Asmari AI, Tabrez S, Henderson C, Watson D, Grant MH (2023) Metabolites, 13: 698. 93



Curcumin and plumbagin synergistically target the PI3K/Akt/mTOR pathway: A prospective role in cancer treatment. by Ahmad I, Hoque M, Alam SSM, Zughaibi TA, Tabrez S*. (2023) International Journal of Molecular Sciences, 24 (7): 6651. 94



Comparative efficacy of epigallocatechin gallate and its nano-formulation in prostate cancer 3D spheroids model. by Alserihi, RF, Mohammed MRS, Kaleem M, Khan MI, Sechi M, Zughaibi TA, Tabrez S*. (2023) Journal of King Saud University Science, 35 (4): 102627. 95



Phenolic acids-mediated regulation of molecular targets in ovarian cancer: Current understanding and future perspectives. by Nazam N, Jabir NR, Ahmad I, Alharthy SA, Khan MS, Ayub R, Tabrez S*. (2023) Pharmaceuticals, 16: 274. 96



Assessment of groundwater geochemistry for drinking and irrigation suitability in Jaunpur district of Uttar Pradesh using GIS-based statistical inference. by Maurya PK, Ali SA, Zaidi SK, Wasi S, Tabrez S, Malav LC, Dittakit P, Son CT, Cabral-Pinto MMS, Yadav KK. (2023)Environmental Science and Pollution Research, 30 (11): 29407-29431. 97



Clinical resistant strains of Enterococci and their correlation to reduced susceptibility to biocides: phenotypic and genotypic analysis of macrolides, lincosamides, and streptogramins. by Lila ASA, Alharby TN, Nafea T, Alanazi J, Alanazi M, Abdallah MH, Rizvi SMD, Moin A, Khafagy El-S, Tabrez S, Al Balushi AA, Hegazy WAH. (2023) Antibiotics 12: 461. 98



Mirtazapine attenuated cadmium-induced neuronal intoxication by regulating Nrf2 and NF-κB/TLR4 signals. by Alharthy SA, Zughaibi TA, Vij P, Tabrez S, Almashjary MN, Alharthi S, Alamri T, Alghamdi BS, Harakeh S, Azhari SA, Farsi RM, Althagafy HS, Hassanein EHM. (2023) Toxicology Mechanisms and Methods, 33 (8): 675-687. 99



Biofilm lifestyle in recurrent urinary tract infections. by Lila ASA, Rajab AAH, Abdallah MH, Rizvi SMD, Moin A, Khafagy El-S, Tabrez S, Hegazy WAH. (2023) Life, 13: 148. 100



Prioritization of bioactive compounds envisaging yohimbine as a multi targeted anticancer agent: insight from molecular docking and molecular dynamics simulation. by Jabir NR, Rehman MT, AlAjmi MF, Ahmed BA, Tabrez S*. (2023) Journal of Biomolecular Structure & Dynamics, 41 (20): 10463-10477. 101



Perturbations of cytokine interleukin-6 in correlation with cancer stem cell markers in oral pre-cancerous and cancerous subjects.by Awasthi S, Gupta R, Ahmad S, Tabrez S, Ahmad S. (2023) European Chemical Bulletin, 12 (5): 212-231. 102



Comparison between Blood, Non-Blood Fluids and Tissue Specimens for the Analysis of Cannabinoid Metabolites in Cannabis-Related Post-Mortem Cases by Torki A. Zughaibi, Latifa Al-Qumsani, Ahmed A. Mirza, Amal Almostady, Jude Basrawi, Shams Tabrez, Faiz Alsolami, Rami Al-Makki, Sami Al-Ghamdi, Abdullah Al-Ghamdi, Abdulnasser E. Alzahrani, Majda Altowairqi, Hassan Alharbi, Michelle R. Peace, Majed A. Halwani and Ahmed I. Al-Asmari 103



Non-Instrumental Green Analytical Method Based on Surfactant-Assisted Dispersive Liquid – Liquid Microextraction – Thin-Layer Chromatography – Smartphone - Based Digital Image Colorimetry(SA-DLLME-TLC-SDIC) for Determining Favipiravir in Biological Samples.by Jain, B.; Jain, R.; Jaiswal, P.K.; Zughaibi, T.; Sharma, T.; Kabir, A.; Singh, R.; Sharma, S. A 104



Statistical analysis, source apportionment, and toxicity of particulate- and gaseous-phase PAHs in the urban atmosphere.by Singh BP, Zughaibi TA, Alharthy SA, Al-Asmari AI and Rahman S (2023) 105



Heroin-Related Fatalities in Jeddah, Saudi Arabia, between 2008 and 2018.by Al-Asmari, A.I.; Alharbi, H.; Al-Zahrani, A.E.; Zughaibi, T.A. 106



Potential inflammatory targets in the integrative health care of patients with sickle cell disease.by Khan, S.A., Halawani, S.H., Zughaibi, T.A., & Khan, S.A. (2023). 107



Magnet Integrated Fabric Phase Sorptive Extraction for the Extraction of Resin Monomers from Human Urine Prior to HPLC Analysis. by Antoniou, G.; Alampanos, V.; Kabir, A.; Zughaibi, T.; Furton, K.G.; Samanidou, V. 108



Cellulose Paper Sorptive Extraction (CPSE) Combined with Gas Chromatography–Mass Spectrometry (GC–MS) for Facile Determination of Lorazepam Residues in Food Samples Involved in Drug Facilitated Crimes. by Jain, B.; Jain, R.; Kabir, A.; Ghosh, A.; Zughaibi, T.; Chauhan, V.; Koundal, S.; Sharma, S. 109



Exploring the potential of fabric phase sorptive extraction in postmortem toxicology: Green analysis of pheniramine in a forensic case of its fatal intoxication, by Rajeev Jain, Abuzar Kabir, Bayan E. Ainousah, Mohammed M. Ghoneim, Torki Zughaibi, Vimukti Chauhan, Sheetal, 110



Exploiting the potential of fabric phase sorptive extraction for forensic food safety: Analysis of food samples in cases of drug facilitated crimes,by Bharti Jain, Rajeev Jain, Abuzar Kabir, Torki Zughaibi, Atul Bajaj, Shweta Sharma, 111



11-Nor-9-Carboxy Tetrahydrocannabinol Distribution in Fluid from the Chest Cavity in Cannabis-Related Post-Mortem Cases. by Zughaibi, T.A.; Alharbi, H.; Al-Saadi, A.; Alzahrani, A.E.; Al-Asmari, A.I. 112



Novel capsule phase microextraction - Gas chromatography - Mass spectrometry for analysis of pheniramine in a case of its fatal intoxication by Bharti Jain, Rajeev Jain, Abuzar Kabir, Torki Zughaibi, SK Manirul Haque, Shweta Sharma, 113



Screening of Cu4O3 NPs efficacy and its anticancer potential against cervical cancer. by Zughaibi, TA, Jabir, NR, Khan, AU, Khan, MS, Tabrez, S. 114



A Natural Repository of Vital Phytochemical and Pharmacological Compounds.by Bhat, A.A., Shakeel, A., Rafiq, S., Farooq, I., Malik, A.Q., Alghuthami, M.E., Alharthi, S., Qanash, H. and Alharthy, S.A., 2023. Juglans regia Linn 115



Investigating the Physical Properties of Thallium-Based Ternary TlXF3 (X= Be, Sr) Fluoroperovskite Compounds for Prospective Applications by Ayub, G., Rauf, A., Husain, M., Algahtani, A., Tirth, V., Al-Mughanam, T., Alghtani, A.H., Sfina, N., Rahman, N., Sohail, M. and Khan, R., 2023. 116



Application of ZnO-NRs@ Ni-foam substrate for electrochemical fingerprint of arsenic detection in water. by Rauf, M., Shah, S.K., Algahtani, A., Tirth, V., Alghtani, A.H., Al-Mughanam, T., Hayat, K., Al-Shaalan, N.H., Alharthi, S., Alharthy, S.A. and Amin, M.A., 2023. 117



Current status and vision of local pharmaceutical industries in Saudi Arabia: The focus on nanomedicines by Abdulrahman A. Halwani, Bander Balkhi, Abdullah A. Alamoudi, Nada H. Almozain, Areej M. Alajmi, Abdulwahab Noorwali, Moutaz Y. Badr, Ahmad O. Noor, Alaa Bagalagel, Essam A. Tawfik ,Saudi Pharmaceutical Journal Volume 31, Issue 8, August 2023, 101674 118



Association between laboratory markers and Covid-19 disease severity and outcome: a retrospective cohort study in Saudi Arabia by Aliaa Amr Alamoudi, Sahar Eldakhakhny, Haneen Banjar, Ghada Ajabnoor, Sama Badr Aljohani, Rasha Ramadan Basheer, Basmah Eldakhakhny, Mazen Badawi, Ayman Elsamanoudy , Front. Immunol., 11 July 2023 Sec. Viral Immunology Volume 14 - 2023 119



In silico Screening and Validation of Achyranthes aspera as a Potential Inhibitor of BRAF and NRAS in Controlling Thyroid Cancer, Author(s): Ahmad M. Alamri, Faris A. Alkhilaiwi, Najeeb U. Khan and Munazzah Tasleem Volume 23, Issue 19, 2023 120



In vitro studies on the pharmacological potential, anti-tumor, antimicrobial, and acetylcholinesterase inhibitory activity of marine-derived Bacillus velezensis AG6 exopolysaccharide† Check for updates by Maha A. Alharbi,a Amani A. Alrehaili, Mona Othman I. Albureikan, Amal F. Gharib, Hussam Daghistani, Maha M. Bakhuraysah, Ghfren S. Aloraini, Mohammed A. Bazuhair, Hayaa M. Alhuthalib and Ahmed Ghareeb 121



Urolithin A's Antioxidative, Anti-Inflammatory, and Antiapoptotic Activities Mitigate Doxorubicin-Induced Liver Injury in Wistar Rats by Shahid Karim, Batoul Madani, Abdulhadi S Burzangi, Mohammed Alsieni, Mohammed A Bazuhair, Maha Jamal, Hussam Daghistani, Mohammed O Barasheed, Huda Alkreathy, Mohammad Ahmed Khan, Lateef M Khan 122



CRISPR/Cas-based Aptasensor as an Innovative Sensing Approaches for Food Safety Analysis: Recent Progresses and New Horizons by Marwah Suliman Maashi 123



Metformin Anti-Tumor Effect and Metabolic Reprogramming in Breast Cancer Cells by Feryal Alharthy, Aliaa Amr Alamoudi, Amina Alnouri, Arwa Alkhuzaee, Ghada Ajabnoor, Mehal AlQriqri, Hoda Gad, Hani Choudhry, Alia Aldahlawi, Rasha Ramadan Basheer 124



Identification of novel interacts partners of ADAR1 enzyme mediating the oncogenic process in aggressive breast cancer 125



Identification of key claudin genes associated with survival prognosis and diagnosis in colon cancer through integrated bioinformatic analysis by Rana A. Alghamdi and Maryam H. Al-Zahrani 126



Preparation and characterization of dextran-zein-curcumin nanoconjugate for enhancement of curcumin bioactivity by N. T. S. Albogamy, Samia F. Aboushoushah, F. Aljoud, H. Organji & Nihal S. Elbialy 127



SOX9 Expression Is Increased in Alzheimer’s Disease (AD) and Is Associated With Disease Progression and APOE4 Genotype: A Computational Approach 128



Evaluation of Cytotoxicity of the Methanolic Extract of Red Sea Marine Sponge Xestospongia Testudinaria and Its Related Compounds Against MCF-7 Human Breast Cancer Cells by Alkhilaiwi FA , Fadil SA , Aljoud FA, Yonbawi AR, Ashi A , Hareeri RH, Bakhashab S , Alamri AM, Albikairi AY, Shaala LA , El-Gamal AA, Youssef DT 129



Effect of Nk-lysin peptides on bacterial growth, MIC, antimicrobial resistance, and viral activities 130



Exploring the Validity of Available Markers and Indices in the Diagnosis of Nonalcoholic Fatty Liver Disease (NAFLD) in People with Type 2 Diabetes in Saudi Arabia. Diseases. By Ajabnoor GMA, Bahijri SM, Enani SM, Alsheikh L, Ahmed M, Alhozali A, Al-Shali K, Eldakhakhny BM, Alamoudi AA, Al-Ahmadi J, Borai A, Al-Mowallad AS, Tuomilehto J. 2023 Jan 15;11(1):10. doi: 10.3390/diseases11010010. PMID: 36648875; PMCID: PMC9887592. 131



Novel curcumin nanoformulation induces apoptosis, and reduces migration and angiogenesis in liver cancer cells. By Harakeh S, Saber SH, Al-Raddadi R, Alamri T, Al-Jaouni S, Qari M, Qari Y, Haque S, Zawawi A, Ali SS, Elmageed ZYA, Mousa S. Artif Cells Nanomed Biotechnol. 2023 Dec;51(1):361-370. doi: 10.1080/21691401.2023.2238756. PMID: 37524306. 132



Apoptosis induction in human hepatoma cell line HepG2 cells by trans- Anethole via activation of mitochondria-mediated apoptotic pathways. By Harakeh S, Al-Raddadi R, Alamri T, Al-Jaouni S, Qari M, Qari Y, Kumar A, Tashkandi HM, Moulay M, Aldahlawi AM, Slama P, Haque S. Biomed Pharmacother. 2023 Sep;165:115236. doi: 10.1016/j.biopha.2023.115236. Epub 2023 Jul 31. PMID: 37531780. 133



The Effect of Chronic Laxative Use on Lipid Profile and HbA1c: A Hospital-Based Retrospective Study. By Ajabnoor G, Eldakhakhny B, Hashim KT, Alzahrani MM, Eskandarani R, AlQusaibi B, Alqarni AK, Alsulaimani NM, Dahlan M, Enani S, Almoghrabi Y, Alamoudi AA, Alhozali A, Elsamanoudy A.Cureus. 2023 Sep 11;15(9):e45055. doi: 10.7759/cureus.45055. PMID: 37829969; PMCID: PMC10567100. 134



Prevalence and Factors Associated with Metabolic Syndrome among Non-Diabetic Saudi Adults: A Cross-Sectional Study. By Eldakhakhny, B.; Enani, S.; Jambi, H.; Ajabnoor, G.; Al-Ahmadi, J.; Al-Raddadi, R.; Alsheikh, L.; Abdulaal, W.H.; Gad, H.; Borai, A.; et al. Biomedicines 2023, 11, 3242. https://doi.org/10.3390/biomedicines11123242 135



Vitamin A: A Key Inhibitor of Adipocyte Differentiation y Malibary MA., PPAR Research, vol. 2023, Article ID 7405954, 10 pages, 2023. 136



Fibroblast Growth Factor 21: A More Effective Biomarker Than Free Fatty Acids and Other Insulin Sensitivity Measures for Predicting Non-alcoholic Fatty Liver Disease in Saudi Arabian Type 2 Diabetes Patients. By Bahijri S, Eldakhakhny B, Enani S, et al. (December 14, 2023)Cureus 15(12): e50524. doi:10.7759/cureus.50524 137



Molecular Study of the Protective Effect of a Low-Carbohydrate, High-Fat Diet against Brain Insulin Resistance in an Animal Model of Metabolic Syndrome. By Bima A, Eldakhakhny B, Alamoudi AA, Awan Z, Alnami A, Abo-Elkhair SM, Sakr H, Ghoneim FM, Elsamanoudy A. Brain Sci. 2023 Sep 28;13(10):1383. doi: 10.3390/brainsci13101383. PMID: 37891752; PMCID: PMC10605073. 138



Prevalence and Risk Factors for IgE and IgG Cow's Milk Protein Allergies in Saudi Arabia. By Baghlaf M A, Eid N M, Enani S, et al. (December 19, 2023)Cureus 15(12): e50812. doi:10.7759/cureus.50812 139



Abdalal SA, Yukich J, Andrinopoulos K, Alghanmi M, Wakid MH, Zawawi A, Harakeh S, Altwaim SA, Gattan H, Baakdah F, Gaddoury MA, Niyazi HA, Mokhtar JA, Alruhaili MH, Alsaady I, Alhabbab R, Alfaleh M, Hashem AM, Alahmadey ZZ, Keating J. Livelihood activities, human mobility, and risk of malaria infection in elimination settings: a case-control study. Malar J. 2023 Feb 13;22(1):53. 140



Alsaady, I. M., Altwaim, S., Gattan, H. S., Alghanmi, M., Zawawi, A., Ahmedah, H., ... & Azhar, E. I. (2023). Prevalence of permethrin-resistant kdr mutation in head lice (Pediculus humanus capitis) from elementary school students in Jeddah, Saudi Arabia. PeerJ, 11, e16273. 141



Bajrai, L. H., Alandijany, T. A., Alsaady, I., El-Daly, M. M., Tolah, A. M., Khateb, A. M., ... & Azhar, E. I. (2023). Assessing the inhibitory potential of anti-dengue compounds against Japanese encephalitis virus RNA dependent RNA polymerase: an in silico study. J Biomolecular Structure & Dynamics, 1-17. 142



Altwaim SA, Alsaady I, Gattan HS, Alruhaili MH, Alghanmi M, Abdalal SA, Kamaludeen J, Barnawi A. Awareness of Neglected Tropical Diseases Among Medical and Health Sciences Students at King Abdulaziz University, Jeddah: A Cross-Sectional Study. Bahrain Medical Bulletin. 2023; 45(3). 143



Alandijany, T. A., El-Daly, M. M., Tolah, A. M., Bajrai, L. H., Khateb, A. M., Alsaady, I. M., ... & Azhar, E. I. (2023). Investigating the mechanism of action of anti-dengue compounds as potential binders of zika virus RNA-dependent RNA polymerase. Viruses, 15(7), 1501. 144



Dubey, A., Alawi, M. M., Alandijany, T. A., Alsaady, I. M., Altwaim, S. A., Sahoo, A. K., ... & Azhar, E. I. (2023). Exploration of microbially derived natural compounds against monkeypox virus as viral core cysteine proteinase inhibitors. Viruses, 15(1), 251. 145



Al-Numaani SA, Al-Nemari AT, El-Kafrawy SA, Hassan AM, Tolah AM, Alghanmi M, Zawawi A, Masri BE, Hindawi SI, Alandijany TA, Bajrai LH, Bukhari A, Mahmoud AB, Al Salem WS, Algaissi A, Charrel RN, Azhar EI, Hashem AM. Seroprevalence of Toscana and sandfly fever Sicilian viruses in humans and livestock animals from western Saudi Arabia. One Health. 2023 Jul 11;17:100601. doi: 10.1016/j.onehlt.2023.100601. PMID: 37520847; PMCID: PMC10372353. 146



Alandijany TA, El-Daly MM, Tolah AM, Bajrai LH, Khateb AM, Kumar GS, Dubey A, Dwivedi VD, Azhar EI. A multi-targeted computational drug discovery approach for repurposing tetracyclines against monkeypox virus 147



Bahaddad, S. A., Almalki, M. H. K., Alghamdi, O. A., Sohrab, S. S., Yasir, M., Azhar, E. I., & Chouayekh, H. (2023). Bacillus Species as Direct-Fed Microbial Antibiotic Alternatives for Monogastric Production, 15(1), 1–16. https://doi.org/10.1007/s12602-022-09909-5 148



Bahaddad, S. A., Almalki, M. H. K., Alghamdi, O. A., Sohrab, S. S., Yasir, M., Azhar, E. I., & Chouayekh, H. (2023). Bacillus Species as Direct-Fed Microbial Antibiotic Alternatives for Monogastric Production, 15(1), 1–16. https://doi.org/10.1007/s12602-022-09909-5 149



Sohrab SS, El-Kafrawy SA, Mirza Z, Hassan AM, Alsaqaf F, Azhar EI. Computational Design and Experimental Evaluation of MERS-CoV siRNAs in Selected Cell Lines. 150



Sayed S. Sohrab, Sherif A. El-Kafrawy, Zeenat Mirza, Ahmed M. Hassan, Fatima Alsaqaf, Esam I. Azhar (2023). Delivery of siRNAs against MERS-CoV in Vero and HEK-293 cells: A comparative evaluation of transfection reagents. Journal of King Saud University - Science. https://doi.org/10.1016/j.jksus.2023.102540 IF-3.829 151



Alandijany TA. Respiratory viral infections during Hajj seasons. J Infect Public Health. 2023 Apr 11:S1876-0341(23)00126-0. doi: 10.1016/j.jiph.2023.04.006. Epub ahead of print. PMID: 37085376. 152



El-Daly MM, Al-Raddadi R, Alharbi A, Azhar AE, Khallaf AM, Hassan AM, Alwafi OM, Shabouni OI, Alandijany TA, Li TC, El-Kafrawy SA, Zumla A, Azhar EI. Hepatitis E Virus (HEV) in Makkah, Saudi Arabia: A Population-Based Seroprevalence Study. Viruses. 2023 Feb 9;15(2):484. doi: 10.3390/v15020484. PMID: 36851698; PMCID: PMC9964995. 153



Faizo AA, Bawazir AA, Almashjary MN, Hassan AM, Qashqari FS, Barefah AS, El-Kafrawy SA, Alandijany TA, Azhar EI. Lack of Evidence on Association between Iron Deficiency and COVID-19 Vaccine-Induced Neutralizing Humoral Immunity. Vaccines (Basel). 2023 Feb 1;11(2):327. doi: 10.3390/vaccines11020327. PMID: 36851205; PMCID: PMC9965425. 154



Singh BP, Sohrab SS, Athar M, Alandijany TA, Kumari S, Nair A, Kumari S, Mehra K, Chowdhary K, Rahman S, Azhar EI. Substantial Changes in Selected Volatile Organic Compounds (VOCs) and Associations with Health Risk Assessments in Industrial Areas during the COVID-19 Pandemic. Toxics. 2023 Feb 9;11(2):165. doi: 10.3390/toxics11020165. PMID: 36851040; PMCID: PMC9963041. 155



Kabrah SM, Alandijany TA, Felimban RI, Alserihi RF, Theyab A, Ebid GT. The Prevalence of Transfusion-Transmitted Infection Markers among Blood Donors at Saudi Hospital, Makkah. Clin Lab. 2023 Feb 1;69(2). doi: 10.7754/Clin.Lab.2022.220427. PMID: 36787548. 156



Faizo AA, Qashqari FS, El-Kafrawy SA, Barasheed O, Almashjary MN, Alfelali M, Bawazir AA, Albarakati BM, Khayyat SA, Hassan AM, Alandijany TA, Azhar EI. A potential association between obesity and reduced effectiveness of COVID-19 vaccine-induced neutralizing humoral immunity. J Med Virol. 2023 Jan;95(1):e28130. doi: 10.1002/jmv.28130. Epub 2022 Sep 14. PMID: 36068377; PMCID: PMC9539352. 157



Alzahrani MM, Bamashmous S, Alkharobi H, Alghamdi A, Alharbi RH, Hassan AM, Darwish M, Bukhari A, Mahmoud AB, Alfaleh MA, Mirza AA, Abuzenadah AM, Abujamel TS, Hashem AM. Mouth rinses efficacy on salivary SARS-CoV-2 viral load: A randomized clinical trial. J Med Virol. 2023 Jan;95(1): e28412. 158



El-Kafrawy SA, Abbas AT, Oelkrug C, Tahoon M, Ezzat S, Zumla A, Azhar EI. IgY antibodies: The promising potential to overcome antibiotic resistance. Frontiers in Immunology 14 (2023): 1065353. 159



Neamatallah T, El-Shitany N, Abbas A, Eid BG, Harakeh S, Ali S, Mousa S. Correction: Neamatallah et al. Nano Ellagic Acid Counteracts Cisplatin-Induced Upregulation in OAT1 and OAT3: A Possible Nephroprotection Mechanism. Molecules 2020, 25, 3031. Molecules 2023; 28(15): 5626. 160



Yasir M, Al-Sharif HA, Al-Subhi T, Sindi AA, Bokhary DH, El-Daly MM, Alosaimi B, Hamed ME, Karim AM, Hassan AM, AlShawdari MM, Alawi M, El-Kafrawy SA, Azhar EI. Analysis of the nasopharyngeal microbiome and respiratory pathogens in COVID-19 patients from Saudi Arabia. J Infect Public Health. 2023 May;16(5):680-688. doi: 10.1016/j.jiph.2023.03.001. 161



Abdulkareem AA, Zaman Q, Khan H, Khan S, Rehman G, Tariq N, Ahmad M, Owais M, Najumuddin, Osama Yousef Muthaffar, Bibi F, Khang R, Ryu SW, Naseer MI, Musharraf Jelani M. Whole exome sequencing identified five novel variants in CNTN2, CARS2, ARSA, and CLCN4 leading to epilepsy in consanguineous families. 162



Zaman Q, Iftikhar A, Rehman G, Khan Q, Najumuddin, Jan A, Khan J, Anas M, Laiba, Umair M, Muthaffar OY, Abdulkareem AA, Bibi F, Naseer MI, Jelani M. Two novel homozygous variants of ATP6V0A2 and ALDH18A1 lead to autosomal recessive cutis laxa type 2 and 3 in two Pakistani families 163



Rahat MA, Akbar F, Rasool A, Ilyas M, Rakha A, Shams S, Jelani M, Bibi F, Shirah BH, Abdulkareem AA, Naseer MI, Israr M. Phenotypic Classification of Eye Colour and Developmental Validation of the Irisplex System on Population Living in Malakand Division, Pakistan 164



Bibi F, Naseer MI, Azhar EI. Exploring bioactive compounds from a symbiotic bacterial strain of Spongiobacter sp 165



Algahtani H, Shirah B, Abdulkareem AA, Bibi F, Pushparaj PN, Naseer MI. Leber hereditary optic neuropathy presenting as bilateral visual loss and white matter disease 166



Iqbal M, Shams S, Rafiq H, Khan M, Khan S, Khattak US, Afridi SG, Bibi F, Abdulkareem AA, Naseer MI. Combinatorial Therapeutic Potential of Stem Cells and Benzimidazol Derivatives for the Reduction of Liver Fibrosis 167



Zaman Q, Khan MA, Sahar K, Rehman G, Khan H, Rehman M, Najumuddin, Ahmad I, Tariq M, Muthaffar OY, Abdulkareem AA, Bibi F, Naseer MI, Faisal MS, Wasif N, Jelani M. Novel Variants in MPV17, PRX, GJB1, and SACS Cause Charcot-Marie-Tooth and Spastic Ataxia of Charlevoix-Saguenay Type Diseases 168



Zaman Q, Sadeeda, Anas M, Rehman G, Khan Q, Iftikhar A, Ahmad M, Owais M, Ahmad I, Muthaffar OY, Abdulkareem AA, Bibi F, Jelani M, Naseer MI. Report of Hermansky-Pudlak Syndrome in Two Families with Novel Variants in HPS3 and HPS4 Genes 169



Aldriwesh MG, Al-Mutairi AM, Alharbi AS, Aljohani HY, Alzahrani NA, Ajina R, Alanazi AM. Paediatric Asthma and the Microbiome: A Systematic Review. 170



Alharbi AS, Altwaim SA, Alharbi AS, Alsulami S. Interplay Between Sociodemographic Variables, Physical Activity, Sleep, Dietary Habits, and Immune Health Status: A Cross-Sectional Study from Saudi Arabia's Western Province. 171



Alharbi AS. Immune fitness and lifestyle habits of Saudi medical students: a cross sectional study. 172



Alharbi MT, Almuhayawi MS, Nagshabandi MK, Tarabulsi MK, Alruhaili MH, Gattan HS, Al Jaouni SK, Selim S, Alanazi A, Alruwaili Y, Zaied SM, Faried OA. Antimicrobial Resistance Pattern, Pathogenicity and Molecular Properties of Hypervirulent Klebsiella pneumonia (hvKp) among Hospital-Acquired Infections in the Intensive Care Unit (ICU). 173



Altwaim, S.A., El-Shimi, O.S., Ismail, K.A., Abdelwahab, M.M., Hagag, H.M., Al Thomali, A.M., Asseeri, A.A., Alharbi, A.S., Alturkistani, A., Alkhamash, A.H. and Alsofyani, M.H. Exploration of Infectious causes of Miscarriage In Taif City, Saudi Arabia. BIOSCIENCE RESEARCH, 2023 20(3):904-910. 174



Ali M, Al-Ahmadi BM, Ibrahim R, Alahmadi S, gattan H, shater AF, elshazly H. Hard ticks (acari: ixodidae) infesting arabian camels (camelus dromedarius) in medina and qassim, saudi arabia. 175



Almuhayawi MS, Alruhaili MH, Gattan HS, Alharbi MT, Nagshabandi M, Al Jaouni S, Selim S, Alanazi A, Alruwaili Y, Faried OA, Elnosary ME. Staphylococcus aureus Induced Wound Infections Which Antimicrobial Resistance, Methicillin- and Vancomycin-Resistant: Assessment of Emergence and Cross Sectional Study. 176



Almuhayawi MS, Alruhaili MH, Gattan HS, Alharbi MT, Nagshabandi MK, Almehayawi MS, Jaouni SKA, Selim S, Alqahtani FS, El-Saadony MT, Alagawany M. Evaluation of antimicrobial effect of olive leaves powder and its role in improving the broiler productivity, carcass traits, blood metabolites, and caecal microbiota. 177



Almuhayawi MS, Gattan HS, Alruhaili MH, Alharbi MT, Nagshabandi MK, Tarabulsi MK, Almuhayawi SM, Al Jaouni SK, Selim S, Alanazi A, Alruwaili Y, Faried OA, Amin I, Elnosary ME. Molecular Profile and the Effectiveness of Antimicrobials Drugs Against Staphylococcus aureus and Pseudomonas aeruginosa in the Diagnostic Approaches of Otitis Infection. 178



Al-Nakhle HH, Khateb AM. Comprehensive In Silico Characterization of the Coding and Non-Coding SNPs in Human Dectin-1 Gene with the Potential of High-Risk Pathogenicity Associated with Fungal Infections. 179



Alqarni AS, Wakid MH, Gattan HS. Hygiene practices and factors influencing intestinal parasites among food handlers in the province of Belgarn, Saudi Arabia. 180



Al-Rajhi AMH, Qanash H, Almashjary MN, Hazzazi MS, Felemban HR, Abdelghany TM. Anti-Helicobacter pylori, Antioxidant, Antidiabetic, and Anti-Alzheimer's Activities of Laurel Leaf Extract Treated by Moist Heat and Molecular Docking of Its Flavonoid Constituent, Naringenin, against Acetylcholinesterase and Butyrylcholinesterase. 181



Alruhaili MH, Almuhayawi MS, Gattan HS, Alharbi MT, Nagshabandi MK, Jaouni SKA, Selim S, AbdElgawad H. Insight into the phytochemical profile and antimicrobial activities of Amomum subulatum and Amomum xanthioides: an in vitro and in silico study. 182



Alsaady IM, Bajrai LH, Alandijany TA, Gattan HS, El-Daly MM, Altwaim SA, Alqawas RT, Dwivedi VD, Azhar EI. Cheminformatics Strategies Unlock Marburg Virus VP35 Inhibitors from Natural Compound Library. Viruses, 15(8), 1739. 183



Alshammari A, Gattan HS, Marzok M, Salem M, Al-Jabr OA, Selim A. Fasciola hepatica Infection in Horses in Three Governorates in Northern Egypt: Prevalence and Risk Factors. 184



Alshammari A, Gattan HS, Marzok M, Selim A. Seroprevalence and risk factors for Neospora spp. infection in equine in Egypt. 185



Alsulami MN, Mohamed K, Wakid MH, Abdel-Gaber R, Timsah AG, Al-Megrin WAI, Khan A, Elkholy WA, Abdelaal KAA, Elshabrawy HA, El-Kady AM. Molecular Characterization of Fasciola hepatica in Sheep Based on DNA Sequences of Ribosomal ITS-1. 186



Al-Zahrani IA. Cloinridioides (Clostridium) difficile: A silent nosocomial pathogen. 187



AlZahrani WM, AlGhamdi SA, Sohrab SS, Rehan M. Investigating a Library of Flavonoids as Potential Inhibitors of a Cancer Therapeutic Target MEK2 Using in Silico Methods. 188



Ashoor SJ, Wakid MH. Prevalence and hepatic histopathological findings of fascioliasis in sheep slaughtered in Jeddah, Saudi Arabia. 189



Azhar EI, Velavan TP, Rungsung I, Traore T, Hui DS, McCloskey B, El-Kafrawy SA, Zumla A. Middle East respiratory syndrome coronavirus-a 10-year (2012-2022) global analysis of human and camel infections, genomic sequences, lineages, and geographical origins. 190



Bazaid AS, Alsolami A, Patel M, Khateb AM, Aldarhami A, Snoussi M, Almusheet SM, Qanash H. Antibiofilm, Antimicrobial, Anti-Quorum Sensing, and Antioxidant Activities of Saudi Sidr Honey: In Vitro and Molecular Docking Studies. 191



Brek T, Alghamdi AK, Abujamel TS, Yasir M, Alattas EM, Hazazi MS, Al-Zahrani IA. Prevalence and molecular determinants of carbapenemase-producing Klebsiella pneumoniae isolated from Jazan, Saudi Arabia. 192



Chouhan M, Tiwari PK, Moustafa M, Chaubey KK, Gupta A, Kumar R, Sahoo AK, Azhar EI, Dwivedi VD, Kumar S. Inhibition of Mycobacterium tuberculosis resuscitation-promoting factor B (RpfB) by microbially derived natural compounds: a computational study. 193



El-Kady AM, S Hassan A, Mohamed K, Alfaifi MS, Elshazly H, Alamri ZZ, Wakid MH, Gattan HS, Altwaim SA, Al-Megrin WAI, Younis S. Zinc oxide nanoparticles produced by Zingiber officinale ameliorates acute toxoplasmosis-induced pathological and biochemical alterations and reduced parasite burden in mice model. 194



El-Wakil ES, Abdelmaksoud HF, Wakid MH, Alsulami MN, Hammam O, Albohiri HH, Ghallab MMI. Annona muricata Leaf as an Anti-Cryptosporidial Agent: An In Silico Molecular Docking Analysis and In Vivo Studies. 195



Gattan HS, Alawi MM, Bajrai LH, Alandijany TA, Alsaady IM, El-Daly MM, Dwivedi VD, Azhar EI. A Multifaceted Computational Approach to Understanding the MERS-CoV Main Protease and Brown Algae Compounds’ Interaction. 196



Gattan HS, Alshammari A, Marzok M, Salem M, Al-Jabr OA, Selim A. Prevalence of Cryptosporidium infection and associated risk factors in calves in Egypt. 197



Ghazawy NAR, Afify A, Radwan IT, Ghabban H, Alkhaibari AM, Gattan HS, Alruhaili MH, Selim A, Saad MMA. The Effect of Abamectin on Locusta Migratoria Neurosecretory Cells and Mid Gut, Using Ultrastructure Examination, Oxidative Stress Study, and In-Silico Molecular Docking. 198



Gupta A, Dutt V, Sharma N, Kajale S, Bhatt A, Shafi S, Azhar E, Zumla A, Sharma A. Examining the microbial composition of natural springs in Bhaderwah, Jammu and Kashmir, India. 199



Hindawi S, Elgemmezi T, El-Kafrawy SA, Samadani H, Tilmisani M, Assiri O, Raml M, Azhar EI, Badawi M. Assessment of the impact of pathogen reduction technologies on the neutralizing activity of COVID-19 convalescent plasma. 200



Iftikhar S, Karim AM, Karim AM, Karim MA, Aslam M, Rubab F, Malik SK, Kwon JE, Hussain I, Azhar EI, Kang SC, Yasir M. Prediction and interpretation of antibiotic-resistance genes occurrence at recreational beaches using machine learning models. 201



Javed M, Bukhari RS, Rasool R, Alhomrani M, Alghamdi SA, Habeeballah H, Ramzan F, Baothman BK, Kashif M, Almaghrabi S, Izmirly AM, Khalid SY. Screening of four signature genes for clinical testing through bioinformatics and in vitro methods in head and neck squamous cell carcinoma. 202



Khateb A, Gago S, Bromley M, Richardson M, Bowyer P. Aneuploidy Is Associated with Azole Resistance in Aspergillus fumigatus. 203



Khateb AM, Alkhaibari SA. Cross-sectional investigation of mycological diagnosis challenges in Saudi Arabia. 204



Kumar GS, Dubey A, Panda SP, Alawi MM, Sindi AA, Azhar EI, Dwivedi VD, Agrawal S. Repurposing of antibacterial compounds for suppression of Mycobacterium tuberculosis dormancy reactivation by targeting resuscitation-promoting factors B. 205



Majeed QAH, Gattan H, Al-Ahmadi BM, Shater AF, Alanazi AD, Alazemi MSH. Acaricidal, larvacidal, and repellent activity of green synthesized silver nanoparticles against Hyalomma dromedarii. 206



Marzok M, Al-Jabr OA, Salem M, Alkashif K, Sayed-Ahmed M, Wakid MH, Kandeel M, Selim A. Seroprevalence and Risk Factors for Toxoplasma gondii Infection in Horses. Batista 207



Memesh R, Yasir M, Ledder RG, Zowawi H, McBain AJ, Azhar EI. An update on the prevalence of colistin and carbapenem-resistant gram-negative bacteria in aquaculture: an emerging threat to public health. 208



Mohamed EFE, Hafez AEE, Seadawy HG, Elrefai MFM, Abdallah K, El Bayomi RM, Mansour AT, Bendary MM, Izmirly AM, Baothman BK, Alwutayd KM, Mahmoud AFA. Irradiation as a Promising Technology to Improve Bacteriological and Physicochemical Quality of Fish. 209



Patel M, Bazaid AS, Azhar EI, Gattan HS, Binsaleh NK, Patel M, Surti M, Adnan M. Novel phytochemical inhibitors targeting monkeypox virus thymidine and serine/threonine kinase: integrating computational modeling and molecular dynamics simulation. 210



Petersen E, Hui DS, Nachega JB, Ntoumi F, Goletti D, Aklillu E, Sharma A, Nyirenda T, Yeboah-Manu D, Satta G, da Costa C, Azhar EI, Bockarie M, Al-Abri S, McHugh TD, Rodriguez-Morales AJ, Varghese GM, Zumla A. End of the Bedaquiline patent - a crucial development for moving forward affordable drugs, diagnostics, and vaccines for infectious diseases in low- and middle-income countries. 211



Qanash H, Bazaid AS, Aldarhami A, Alharbi B, Almashjary MN, Hazzazi MS, Felemban HR, Abdelghany TM. Phytochemical Characterization and Efficacy of Artemisia judaica Extract Loaded Chitosan Nanoparticles as Inhibitors of Cancer Proliferation and Microbial Growth. 212



Selim A, Alshammari A, Gattan HS, Alruhaili MH, Rashed GA, Shoulah S. Seroprevalence and associated risk factors for Toxoplasma gondii in water buffaloes (Bubalus bubalis) in Egypt. 213



Selim A, Alshammari A, Gattan HS, Marzok M, Salem M, Al-Jabr OA. Neospora caninum infection in dairy cattle in Egypt: a serosurvey and associated risk factors. 214



Selim A, Alshammari A, Marzok M, Salem M, Al-Jabr OA, Gattan HS. Molecular prevalence and associated risk factors of Theileria annulata infections in dromedary camels in Egypt. 215



Selim A, Marzok M, Alshammari A, Al-Jabr OA, Salem M, Wakid MH. Toxoplasma gondii infection in Egyptian domestic sheep and goats: seroprevalence and risk factors. 216



Sharma A, McCloskey B, Hui DS, Rambia A, Zumla A, Traore T, Shafi S, El-Kafrawy SA, Azhar EI, Zumla A, Rodriguez-Morales AJ. Global mass gathering events and deaths due to crowd surge, stampedes, crush and physical injuries - Lessons from the Seoul Halloween and other disasters. 217



Sharma A, Rodriguez-Morales AJ, Traore T, Shafi S, El-Kafrawy SA, Azhar EI, Zumla A. Globalisation of antibiotic-resistant bacteria at recurring mass gathering events. 218



Shoulah SA, Gaballa MMS, Marawan MA, Saqr SA, Abdelhady A, Alzahrani HA, Wakid MH, Al-Jabr OA, Selim A. Pathological Findings and Oxidative Stress Status Associated with Hydatidosis in Dromedary Camels. 219



Traore SI, Lo CI, Mossaab M, Durand G, Lagier JC, Raoult D, Fournier PE, Fenollar F. Maliibacterium massiliense gen. nov. sp. nov., Isolated from Human Feces and Proposal of Maliibacteriaceae fam. nov. 220



Yasir M, Alkhaldy AA, Soliman SA, Turkistani SA, Azhar EI. Metagenomic Insights into the Microbiome and Resistance Genes of Traditional Fermented Foods in Arabia. 221



Yehia RS, Altwaim SA. An Insight into In Vitro Antioxidant, Antimicrobial, Cytotoxic, and Apoptosis Induction Potential of Mangiferin, a Bioactive Compound Derived from Mangifera indica. 222



Zahra Q, Gul J, Shah AR, Yasir M, Karim AM. Antibiotic resistance genes prevalence prediction and interpretation in beaches affected by urban wastewater discharge. 223



Genetic Variants in the Mitochondrial Thymidylate Biosynthesis Pathway Increase Colorectal Cancer Risk by Entesar M Arrait, Ayat B Al-Ghafari, Huda A Al Doghaither 224



Role of mitochondrial disruption and oxidative stress in plasticizer phthalate-induced cytotoxicity to human bone osteoblasts by Ekramy Mahmoud Elmorsy, Ayat Al-Ghafari, Huda Al Doghaither 225



5-Fluorouracil and capecitabine therapies for the treatment of colorectal cancer (Review) by Shiekhah M Alzahrani, Huda A Al Doghaither, Ayat B Al-Ghafari, Peter N Pushparaj 226



Possible Inhibition of Renal Protein Glycation by Carnosine and Tocopherol in Diabetic Rat by Etimad Huwait, Maryam A. Al-Ghamdi, Faisal S. Al-Shehri , Said S. Moselhy 227



Inhibition of dipeptidyl peptidase-4 (DPP4), antioxidant, antiglycation and anti-inflammatory effect of Ferulic acid against streptozotocin toxicity mediate nephropathy in diabetic rats 228



Therapeutic effect of combination vitamin D3 and siponimod on remyelination and modulate microglia activation in cuprizone mouse model of multiple sclerosis by Kholoud M. Al-Otaibi, Badrah S. Alghamdi, Maryam A. Al-Ghamdi, Rasha A. Mansouri1 Ghulam Md Ashraf, Ulfat M. Omar1 229



Thymoquinone ameliorates acrylamide-induced reproductive toxicity in female rats: An experimental study by Maryam AL-ghamdi1, Etimad Huwait, Nagwa Elsawi, Soad Shaker Ali, Ahmed Sayed 230



Rhus tripartite methanolic extract alleviates propylparaben-induced reproductive toxicity via anti-inflammatory, antioxidant, 5-α reductase in male rats. by Mosaoa, R.M., Kumosani, T.A., Yaghmoor, S.S. et al. Environ Sci Pollut Res 30, 76969–76976 231



Atheroprotective Effect of Fucoidan in THP-1 Macrophages by Potential Upregulation of ABCA1 by Zeenat Mirza, Dalal A. Al-Saedi, Salma Saddeek, Sanaa Almowallad, Rehab F. AlMassabi and Etimad Huwait 232



Integration of palliative care in the management of oral squamous cell carcinoma Republica et al. Bioinformation 19(1): 1-4 (2023) 233



Microarray Expression Profile of Myricetin-Treated THP-1 Macrophages Exhibits Alterations in Atherosclerosis-Related Regulator Molecules and LXR/RXR Pathway by Etimad Huwait, Rehab Almassabi, Sanaa Almowallad, Salma Saddeek, Sajjad Karim, Gauthaman Kalamegam and Zeenat Mirza 234



Identification of novel interacts partners of ADAR1 enzyme mediating the oncogenic process in aggressive breast cancer by Najat Binothman, Majidah Aljadani, Bandar Alghanem, Mohammed Y. Refai, Mamoon Rashid, Abeer Al Tuwaijri, Nouf H. Alsubhi, Ghadeer I. Alrefaei, Muhammad Yasir Khan, Sultan N. Sonbul, Fadwa Aljoud, Sultan Alhayyani, Rwaa H. Abdulal, Magdah Ganash & Anwar M. Hashem 235



Optimal Deep Transfer Learning Based Colorectal Cancer Detection and Classification Model by Mahmoud Ragab, Maged Mostafa Mahmoud, Amer H. Asseri, Hani Choudhry, Haitham A. Yacoub 236



Antioxidant activity and inhibitory effect of 2,4,4'-trihydroxychalcone on digestive enzymes related to obesity Authors Hadeil Alsufiani , Ghaynat A. Aldhaheri , Ulfat M. Omar , Taraji M. Bahdilah , Rasha A. Mansour 237



Salivary Hormones Leptin, Ghrelin, Glucagon, and Glucagon-Like Peptide 1 and Their Relation to Sweet Taste Perception in Diabetic Patients by Nada K. Al-Ghurayr , Ashjan M. Al-Mowalad , Ulfat M. Omar , Heba M. Ashi , Saad S. Al-Shehri , Abdelrahman A. AlShaikh , Shada M. AlHarbi and Hadeil M. Alsufiani 238



A new cirrhotic animal protocol combining carbon tetrachloride with methotrexate to address limitations of the currently used chemical-induced models by Rasha A. Mansouri, Adel M. Ahmed, Huda F. Alshaibi, Maha M. Al-Bazi, Abeer A. Banjabi, Hadeil Muhanna Alsufiani, Akram Ahmed Aloqbi, Esam M. Aboubakr 239



Cell Growth Inhibition, DNA Fragmentation and Apoptosis-Inducing Properties of Household-Processed Leaves and Seeds of Fenugreek (Trigonella Foenum-Graecum Linn.) against HepG2, HCT-116, and MCF-7 Cancerous Cell Lines by Shaimaa G. Abdel Salam, Mohamed M. Rashed, Nabih A. Ibrahim, Emam A. Abdel Rahim , Hadeil Muhanna Alsufiani , Rasha A. Mansouri, Mohamed Afifi and Ammar Al-Farga 240



Formulation of chrysin loaded nanostructured lipid carriers using Box Behnken design, its characterization and antibacterial evaluation alone and in presence of probiotics co-loaded in gel, by Shaik Rahana Parveen, Sheetu Wadhwa, Molakpogu Ravindra Babu, Sukriti Vishwas, Leander Corrie, Ankit Awasthi, Farhan R. Khan, Maha M. Al-Bazi, Nahed S. Alharthi, Faisal Alotaibi, Gaurav Gupta, Narendra Kumar Pandey, Bimlesh Kumar, Popat Kumbhar, John Disouza, Monica Gulati, Jayanthi Neelamraju, Ratna Sudha Madempudi, Kamal Dua, Sachin Kumar Singh, Journal of Drug Delivery Science and Technology,Volume 84,2023,104411 241



Protective effect of barbigerone against ethanol-induced ulcers via the interleukins/ICAM-1/Bcl-2 pathway by European Review for Medical and Pharmacological Sciences 27 (2023): 12029-12042. 242



Influence of rosiridin on streptozotocin-induced diabetes in rodents through endogenous antioxidants-inflammatory cytokines pathway and molecular docking study, by Imran Kazmi, Fahad A. Al-Abbasi, Shareefa A. AlGhamdi, Amira M. Alghamdi, Mustafa Zeyadi, Ryan A. Sheikh, Gaurav Gupta & Nadeem Sayyed (2023) Journal of Biomolecular Structure and Dynamics, DOI: 10.1080/07391102.2023.2282738 243



Raman SNT, Zetner A, Hashem AM, Patel D, Wu J, Gravel C, Gao J, Zhang W, Pfeifle A, Tamming L, Parikh K, Cao J, Tam R, Safronetz D, Chen W, Johnston MJW, Wang L, Sauve S, Rosu-Myles M, Domselaar GV, Li X. Bivalent vaccines effectively protect mice against influenza A and respiratory syncytial viruses. Emerg Microbes Infect. 2023 Dec;12(1):2192821. doi: 10.1080/22221751.2023.2192821. 244



Wagstaff JM, Planelles-Herrero VJ, Sharov G, Alnami A, Kozielski F, Derivery E, Löwe J. Diverse cytomotive actins and tubulins share a polymerization switch mechanism conferring robust dynamics. Sci Adv. 2023 Mar 29;9(13):eadf3021. doi: 10.1126/sciadv.adf3021. 245



Alzahrani MM, Bamashmous S, Alkharobi H, Alghamdi A, Alharbi RH, Hassan AM, Darwish M, Bukhari A, Mahmoud AB, Alfaleh MA, Mirza AA, Abuzenadah AM, Abujamel TS, Hashem AM. Mouth rinses efficacy on salivary SARS-CoV-2 viral load: A randomized clinical trial. J Med Virol. 2023 Jan;95(1):e28412. doi: 10.1002/jmv.28412. 246



Shuaib M, Adroub S, Mourier T, Mfarrej S, Zhang H, Esau L, Alsomali A, Alofi FS, Ahmad AN, Shamsan A, Khogeer A, Hashem AM, Almontashiri NAM, Hala S, Pain A. Impact of the SARS-CoV-2 nucleocapsid 203K/204R mutations on the inflammatory immune response in COVID-19 severity. Genome Med. 2023 Jul 21;15(1):54. doi: 10.1186/s13073-023-01208-0 247



Alhabbab RY, Algaissi A, Mahmoud AB, Alkayyal AA, Al-Amri S, Alfaleh MA, Basabrain M, Alsubki RA, Almarshad IS, Alhudaithi AM, Gafari OAA, Alshamlan YA, Aldossari HM, Alsafi MM, Bukhari A, Bajhmom W, Memish ZA, Al Salem WS, Hashem AM. Middle East Respiratory Syndrome Coronavirus Infection Elicits Long-lasting Specific Antibody, T and B Cell Immune Responses in Recovered Individuals. Clin Infect Dis. 2023 Feb 8;76(3):e308-e318. doi: 10.1093/cid/ciac456. 248



Altorki TA, Abdulal RH, Suliman BA, Aljeraisi TM, Alsharef A, Abdulaal WH, Alfaleh MA, Algaissi AA, Alhabbab RY, Ozbak H, Eid HM, Almutawif YA, Li X, Al-Rabia MW, Zhang Q, Mahmoud AB, Mahallawi WH, Hashem AM. Robust memory humoral immune response to SARS-CoV-2 in the tonsils of adults and children. Front Immunol. 2023 Dec 11;14:1291534. doi: 10.3389/fimmu.2023.1291534. 249



Alfaleh MA, Alsulaiman RM, Almahboub SA, Nezamuldeen L, Zawawi A, Aljehani ND, Yasir M, Abdulaal RH, Alkhaldi R, Helal A, Alamri SS, Malki J, Alhabbab RY, Abujamel TS, Alhakamy NA, Alnami A, Algaissi A, Hassanain M, Hashem AM. ACE2-Fc and DPP4-Fc decoy receptors against SARS-CoV-2 and MERS-CoV variants: A quick therapeutic option for current and future coronaviruses outbreaks. Antibody Therapeutics, 2023;, tbad030, https://doi.org/10.1093/abt/tbad030 250



Harakeh S, Saber SH, Al-Raddadi R, Alamri T, Al-Jaouni S, Qari M, Qari Y, Haque S, Zawawi A, Ali SS, Elmageed ZYA, Mousa S. Novel curcumin nanoformulation induces apoptosis, and reduces migration and angiogenesis in liver cancer cells. Artif Cells Nanomed Biotechnol. 2023 Dec;51(1):361-370. doi: 10.1080/21691401.2023.2238756. 251



Ahmed MM, Fatima F, Alnami A, Alsenaidy M, Aodah AH, Aldawsari MF, Almutairy B, Anwer MK, Jafar M. Design and Characterization of Baricitinib Incorporated PLA 3D Printed Pills by Fused Deposition Modeling: An Oral Pill for Treating Alopecia Areata. Polymers (Basel). 2023 Apr 8;15(8):1825. doi: 10.3390/polym15081825. 252



Yacoub HA, Mahmoud MM, Al-Hejin AM, Abujamel TS, Tabrez S, Abd-Elmaksoud S. Effect of Nk-lysin peptides on bacterial growth, MIC, antimicrobial resistance, and viral activities. Anim Biotechnol. 2023 Dec 15:1-19. doi: 10.1080/10495398.2023.2290520. 253



Mahmoud MM, Al-Hejin AM, Abujamel TS, Ghetas AM, Yacoub HA. Chicken β-defensin-1 peptide as a candidate anticoccidial agent in broiler chickens. Anim Biotechnol. 2023 Dec;34(7):3108-3125. doi: 10.1080/10495398.2022.2136677. 254



Alfaleh MA, Razeeth Shait Mohammed M, Hashem AM, Abujamel TS, Alhakamy NA, Imran Khan M. Extracellular matrix detached cancer cells resist oxidative stress by increasing histone demethylase KDM6 activity. Saudi J Biol Sci. 2024 Jan;31(1):103871. doi: 10.1016/j.sjbs.2023.103871. 255



Abdulal RH, Khan MY, Aljehani ND, Fallata ZI, AlHarbi RH, Alsulaiman RM, Ghazal EA, Basabrain M, Sanki MA, Ganash M, Qadri I, Abdulaal WH, Alrabia MW, Hassanain M, Alfaleh MA, Raman SNT, Tamming L, Altorki T, Abujamel TS, Li X, Algaissi A, Alhabbab RY, Hashem AM. A Modified Recombinant DNA-Based SARS-CoV-2 Vaccine Expressing Stabilized Uncleavable Spike Protein Elicits Humoral and Cellular Immunity against Various SARS-CoV-2 Variants of Concern. Transbound Emerg Dis. 2023, Article ID 5279979, 11 pages. 256



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